Department and Clinic of Vascular, General and Transplantation Surgery, Wroclaw Medical University, Poland.
Department and Clinic of Cardiology, Wroclaw Medical University, Poland.
Adv Clin Exp Med. 2021 Mar;30(3):309-313. doi: 10.17219/acem/133425.
An endoleak is a typical complication of endovascular aneurysm repair (EVAR). It is characterized by persistent blood flow between a stent graft and the aneurysm sac. Usually, it can be visualized during primary EVAR, but in many cases, this remains impossible. Therefore, other methods of endoleak assessment are urgently needed. The measurement of aneurysm sac pressure (ASP) seems to be a promising direction of research in this area.
We aimed to evaluate the safety and efficacy of a new method for invasive pressure measurement inside the abdominal aortic aneurysm (AAA) during EVAR. We also assessed a correlation between pressure values and early angiographic occurrence of an endoleak after the procedure.
A total of 20 patients with AAA were included in this experimental prospective study. During EVAR, systolic, diastolic and mean pressure values were recorded both for ASP and aortic pressure (AP) before procedure, after stent graft opening and after final stent graft ballooning.
The measurements were successfully obtained in all participants without any complications. There were no significant differences between all ASP and AP before procedure. After the procedure, blood pressure significantly decreased in the aneurysm sac but not in the aorta. Systolic ASP was significantly lower than systolic AP both after stent graft opening (80.4 ±20.9 mm Hg compared to 110.7 ±21.6 mm Hg, p < 0.01) and after its balloon post-dilatation (65.6 ±26.1 mm Hg compared to 107.4 ±22.1 mm Hg, p < 0.001). Diastolic ASP decreased significantly in comparison to diastolic AP only after stent graft ballooning (48.0 ±14.6 mm Hg compared to 56.4 ±13.6 mm Hg, p < 0.05).
Our study confirmed that the novel method for the measurement of ASP during EVAR, using a thin pressure wire, is feasible and safe.
内漏是血管内动脉瘤修复术(EVAR)的一种常见并发症。其特征是支架移植物和动脉瘤囊之间持续的血流。通常,它可以在原发性 EVAR 期间可视化,但在许多情况下,这仍然是不可能的。因此,迫切需要其他方法来评估内漏。测量动脉瘤囊压力(ASP)似乎是该领域研究的一个有前途的方向。
我们旨在评估一种新的在 EVAR 期间测量腹主动脉瘤(AAA)内侵袭性压力的方法的安全性和有效性。我们还评估了压力值与术后早期血管造影内漏发生之间的相关性。
这项实验性前瞻性研究共纳入 20 例 AAA 患者。在 EVAR 过程中,在术前、支架移植物打开后和最终支架移植物球囊扩张后,记录 ASP 和主动脉压力(AP)的收缩压、舒张压和平均压值。
所有参与者均成功获得测量值,无任何并发症。在术前,所有 ASP 和 AP 之间均无显著差异。手术后,动脉瘤囊中血压显著下降,但主动脉中血压没有下降。支架移植物打开后,ASP 的收缩压明显低于 AP(80.4 ±20.9 毫米汞柱比 110.7 ±21.6 毫米汞柱,p < 0.01),支架移植物球囊扩张后,ASP 的收缩压明显低于 AP(65.6 ±26.1 毫米汞柱比 107.4 ±22.1 毫米汞柱,p < 0.001)。只有在支架移植物球囊扩张后,ASP 的舒张压才明显低于 AP(48.0 ±14.6 毫米汞柱比 56.4 ±13.6 毫米汞柱,p < 0.05)。
我们的研究证实,使用细压力线测量 EVAR 期间 ASP 的新方法是可行且安全的。