Reese Hannah E, Brown W Alan, Summers Berta J, Shin Jin, Wheeler Grace, Wilhelm Sabine
Department of Psychology, Bowdoin College, 6900 College Station, Brunswick, ME, 04011, USA.
Learning to Thrive, LLC, 300 2nd St., #7, Jersey City, NJ, 07302, USA.
Pilot Feasibility Stud. 2021 Mar 24;7(1):82. doi: 10.1186/s40814-021-00818-y.
Preliminary research suggests that a mindfulness-based treatment approach may be beneficial for adults with tic disorders. In the present study, we report on the feasibility, acceptability, safety, and symptomatic effect of a novel online mindfulness-based group intervention for adults with Tourette syndrome or persistent tic disorder. Data from this study will directly inform the conduct of a funded randomized controlled trial comparing the efficacy of this intervention to another active psychological intervention.
One cohort of adults with Tourette syndrome participated in an 8-week online mindfulness-based group intervention. Measures of feasibility, acceptability, and safety were administered throughout and at posttreatment. Self-reported measures of mindfulness and clinician-rated measures of tic severity and impairment were administered at baseline and posttreatment.
Data on refusal, dropout rate, attendance, participant satisfaction, and safety suggest that this is a feasible and acceptable intervention. However, participant adherence to home practice was lower than anticipated. Mindfulness, tic severity, and tic-related impairment only modestly improved from baseline to posttreatment. Qualitative analysis of participant feedback revealed aspects of the intervention that were most helpful and also areas for improvement.
Data suggest that although this is a feasible and acceptable intervention, it should be modified to enhance participant adherence, more successfully engage the target mechanism, and optimize outcomes.
Clinicaltrials.gov registration # NCT03525626 . Registered on 24 April 2018.
初步研究表明,基于正念的治疗方法可能对患有抽动障碍的成年人有益。在本研究中,我们报告了一种针对患有图雷特综合征或持续性抽动障碍的成年人的新型在线正念团体干预的可行性、可接受性、安全性和症状疗效。本研究的数据将直接为一项资助的随机对照试验的开展提供信息,该试验将比较这种干预与另一种积极心理干预的疗效。
一组患有图雷特综合征的成年人参加了为期8周的在线正念团体干预。在整个干预过程中和治疗后进行可行性、可接受性和安全性测量。在基线和治疗后进行自我报告的正念测量以及临床医生评定的抽动严重程度和损害测量。
关于拒绝率、退出率、出勤率、参与者满意度和安全性的数据表明,这是一种可行且可接受的干预措施。然而,参与者对家庭练习的坚持程度低于预期。从基线到治疗后,正念、抽动严重程度和与抽动相关的损害仅略有改善。对参与者反馈的定性分析揭示了干预中最有帮助的方面以及需要改进的领域。
数据表明,尽管这是一种可行且可接受的干预措施,但应进行修改以提高参与者的坚持程度,更成功地激活目标机制,并优化结果。
Clinicaltrials.gov注册编号#NCT03525626。于2018年4月24日注册。