Department of Medicine, University of Virginia, PO Box 100058, 1215 Lee Street, Charlottesville, VA 22908.
Department of Surgery, University of Virginia, Charlottesville, VA.
Semin Vasc Surg. 2021 Mar;34(1):89-96. doi: 10.1053/j.semvascsurg.2021.02.009. Epub 2021 Feb 4.
Fibromuscular dysplasia is a nonatherosclerotic, under-recognized disorder primarily seen in middle-aged women. It can lead to several complications, such as hypertension, headaches, dissections, aneurysms, myocardial infarctions, and cerebrovascular accidents, to name a few. This article provides a comprehensive review of current literature on epidemiology, etiology, diagnosis, treatment, and long-term surveillance and fibromuscular dysplasia management. In addition, it renders the role of education and prevention for patients living with this condition and family screening. Lastly, it emphasizes the importance of a comprehensive multidisciplinary care model and patient input, given the complexity of this disease and its systemic presence and protean manifestations.
纤维肌性发育不良是一种非动脉粥样硬化性、认识不足的疾病，主要见于中年妇女。它可导致多种并发症，如高血压、头痛、夹层、动脉瘤、心肌梗死和脑血管意外等。本文对纤维肌性发育不良的流行病学、病因、诊断、治疗以及长期监测和管理的最新文献进行了全面回顾。此外，它还阐述了对患有这种疾病的患者及其家属进行教育和预防筛查的重要性。最后，鉴于这种疾病的复杂性及其全身性表现和多变性，强调了综合多学科护理模式和患者参与的重要性。
