Zhang Yi, Wang Ziyue, Cao Yu, Zhang Lifu, Wang Guan, Dong Fangjie, Deng Ren, Guo Baogen, Zeng Li, Wang Peng, Dai Ruimei, Ran Yu, Lyu Wenyi, Miao Peiwen, Su Steven
The School of Aeronautics and Astronautics, University of Electronic Science and Technology of China, Chengdu, 611731 China.
Aircraft Swarm Intelligent Sensing Cooperative Control Key Laboratory of Sichuan Province, University of Electronic Science and Technology of China, Chengdu, 611731 China.
Air Qual Atmos Health. 2021;14(7):1049-1061. doi: 10.1007/s11869-021-00998-9. Epub 2021 Mar 18.
Hospitalisation risks for chronic obstructive pulmonary disease (COPD) have been attributed to ambient air pollution worldwide. However, a rise in COPD hospitalisations may indicate a considerable increase in fatality rate in public health. The current study focuses on the association between consecutive ambient air pollution (CAAP) and COPD hospitalisation to offer predictable early guidance towards estimates of COPD hospital admissions in the event of consecutive exposure to air pollution. Big data analytics were collected from 3-year time series recordings (from 2015 to 2017) of both air data and COPD hospitalisation data in the Chengdu region in China. Based on the combined effects of CAAP and unit increase in air pollutant concentrations, a quasi-Poisson regression model was established, which revealed the association between CAAP and estimated COPD admissions. The results show the dynamics and outbreaks in the variations in COPD admissions in response to CAAP. Cross-validation and mean squared error (MSE) are applied to validate the goodness of fit. In both short-term and long-term air pollution exposures, test outcomes show that the COPD hospitalisation risk is greater for men than for women; similarly, the occurrence of COPD hospital admissions in the group of elderly people (> 65 years old) is significantly larger than that in lower age groups. The time lag between the air quality and COPD hospitalisation is also investigated, and a peak of COPD hospitalisation risk is found to lag 2 days for air quality index (AQI) and PM, and 1 day for PM. The big data-based predictive paradigm would be a measure for the early detection of a public health event in post-COVID-19. The study findings can also provide guidance for COPD admissions in the event of consecutive exposure to air pollution in the Chengdu region.
在全球范围内,慢性阻塞性肺疾病(COPD)的住院风险被认为与环境空气污染有关。然而,COPD住院人数的增加可能表明公共卫生领域的死亡率大幅上升。当前的研究聚焦于连续环境空气污染(CAAP)与COPD住院之间的关联,以便在连续暴露于空气污染的情况下,为COPD住院人数的估计提供可预测的早期指导。大数据分析收集自中国成都地区3年时间序列记录(2015年至2017年)的空气质量数据和COPD住院数据。基于CAAP和空气污染物浓度单位增加的综合影响,建立了一个准泊松回归模型,该模型揭示了CAAP与估计的COPD住院人数之间的关联。结果显示了COPD住院人数变化对CAAP的动态响应和爆发情况。采用交叉验证和均方误差(MSE)来验证拟合优度。在短期和长期空气污染暴露中,测试结果表明,男性的COPD住院风险高于女性;同样,老年人(>65岁)组中COPD住院的发生率明显高于低年龄组。还研究了空气质量与COPD住院之间的时间滞后,发现COPD住院风险峰值在空气质量指数(AQI)和PM方面滞后2天,在PM方面滞后1天。基于大数据的预测范式将是一种在新冠疫情后早期检测公共卫生事件的措施。研究结果还可为成都地区连续暴露于空气污染情况下的COPD住院提供指导。