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**首次报道**：由多育棘孢霉引起的皮肤真菌病，采用伊曲康唑联合特比萘芬联合切除手术治疗，获得成功。

First report of cutaneous mycetoma by Paecilomyces variotii and the successful treatment with combined itraconazole and terbinafine along with resection surgeries.

机构信息

Laboratory of Pathology of Infectious Diseases (LIM-50), Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.

Dermatology Service of Faculdade de Medicina do ABC, Universidade do ABC, Santo André, Sao Paulo, Brazil.

出版信息

Australas J Dermatol. 2021 Aug;62(3):e397-e399. doi: 10.1111/ajd.13592. Epub 2021 Mar 24.

DOI:10.1111/ajd.13592
PMID:33759175
Abstract

Mycetoma is a progressively mutilating infectious disease of the subcutaneous tissue that affects the skin and deep structures, which is poorly responsive to chemotherapy. Here, we report a skin mycetoma caused by Paecilomyces variotii, an uncommon fungus of human infections, and the therapeutic approach that resulted in a complete cure of the patient.

摘要

足菌肿是一种进行性破坏的皮下组织感染性疾病，会影响皮肤和深层组织，对化疗反应不佳。在这里，我们报告了一例由多育巢霉引起的皮肤足菌肿，多育巢霉是人感染的一种不常见真菌，该病例的治疗方法使患者完全康复。

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