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儿童内脏利什曼病多次复发是否可行脾切除术?病例报告。

Is splenectomy an option for multiple relapses in a child with visceral leishmaniasis? A case report.

机构信息

Universidade Federal do Maranhão, Faculdade de Medicina, São Luís, MA, Brasil.

Duke University, Duke Global Health Institute, Durham, North Carolina, United States.

出版信息

Rev Soc Bras Med Trop. 2021 Mar 22;54:e0748-2020. doi: 10.1590/0037-8682-0748-2020. eCollection 2021.

Abstract

Visceral leishmaniasis (VL) is an infectious disease caused by Leishmania spp. The recurrence of the disease occurs, in general, in patients with decreased or loss of T-cell function, whether due to the use of corticosteroids, immunosuppressive disease, or another cause. In some cases, splenectomy may be a therapeutic option. However, the effectiveness of splenectomy is not well defined. This report describes the evolution of a pediatric patient with seven recurrences of VL, who relapsed post-surgery after drug therapy and splenectomy.

摘要

内脏利什曼病(VL)是一种由利什曼原虫引起的传染病。该病的复发通常发生在 T 细胞功能下降或丧失的患者中,无论是由于使用皮质类固醇、免疫抑制性疾病还是其他原因。在某些情况下,脾切除术可能是一种治疗选择。然而,脾切除术的效果尚未得到明确界定。本报告描述了一名儿科患者的病情演变,该患者患有 VL,反复发作 7 次,在药物治疗和脾切除术后手术复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3faa/8008903/dfdfa78f6bfe/1678-9849-rsbmt-54-e0748-2020-gf1.jpg

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