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难治性内脏利什曼病患者行脾切除术:病例报告。

Splenectomy in a patient with treatment-resistant visceral leishmaniasis: a case report.

机构信息

Departamento de Cirurgia Pediátrica, Santa Casa de Franca, Franca, SP.

出版信息

Rev Soc Bras Med Trop. 2012 Feb;45(1):130-1. doi: 10.1590/s0037-86822012000100027.

DOI:10.1590/s0037-86822012000100027
PMID:22370845
Abstract

Visceral leishmaniasis (VL), also known as Kala-azar, is a systemic infection caused by a protozoan (Leishmania) and, in its classic form, is a serious illness associated with malnutrition, anemia, hepatosplenomegaly, infectious processes and coagulopathies. The effect of splenectomy in patients with visceral leishmaniasis is not well defined; however, it is known that the spleen is the largest reservoir of infected cells belonging to the reticulo endothelial system. Therefore, the surgical procedure is an option for the debulking of parasites, providing a cure for refractory VL and minimizing the complications of hypersplenism.

摘要

内脏利什曼病(VL),又称黑热病,是一种由原生动物(利什曼原虫)引起的系统性感染,在其典型形式中,是一种与营养不良、贫血、肝脾肿大、感染过程和凝血功能障碍相关的严重疾病。脾切除术对内脏利什曼病患者的疗效尚未明确界定;然而,众所周知,脾脏是属于网状内皮系统的最大感染细胞库。因此,手术是一种去除寄生虫的方法,可以治愈难治性内脏利什曼病,并最大限度地减少脾功能亢进的并发症。

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Rev Soc Bras Med Trop. 2012 Feb;45(1):130-1. doi: 10.1590/s0037-86822012000100027.
2
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