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肺动脉计算机断层扫描血管造影参数作为肺动脉内膜剥脱术后残余肺动脉高压的预后因素

Computed tomography angiographic parameters of pulmonary artery as prognostic factors of residual pulmonary hypertension after pulmonary endarterectomy.

作者信息

Niznansky Matus, Kavan Jan, Zemankova Petra, Prskavec Tomas, Ambroz David, Jansa Pavel, Lindner Jaroslav

机构信息

Department of Cardiovascular Surgery, General University Hospital in Prague and First Faculty of Medicine, Charles University in Prague, Czech Republic.

Department of Radiology, General University Hospital in Prague and First Faculty of Medicine, Charles University in Prague, Czech Republic.

出版信息

J Int Med Res. 2021 Mar;49(3):3000605211002024. doi: 10.1177/03000605211002024.

Abstract

OBJECTIVES

This study aimed to retrospectively assess using computed tomography pulmonary angiography (CTPA) for predicting residual pulmonary hypertension (RPH) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary endarterectomy (PEA).

METHODS

We retrospectively analyzed data of 131 patients with CTEPH who underwent PEA in our center (2008-2015). We measured several diameters of the pulmonary artery and thoracic aorta preoperatively. We evaluated the relationship between these measurements (and their indices) and signs of RPH represented by pulmonary artery systolic pressure (PASP) estimated by echocardiography.

RESULTS

Significant correlations were observed between the aortopulmonary index and prediction of any residual hypertension and moderate/severe hypertension 1 year after PEA, and any residual hypertension and severe hypertension 2 years after PEA. The aortopulmonary index was significantly related to a reduction in PASP 1 year after the operation. A lower aortopulmonary index (≤0.88 for the ascending aorta and ≤0.64 for the descending aorta) predicted lower RPH.

CONCLUSIONS

Preoperative CTPA parameters can be used to assess the risk of RPH after PEA. The aortopulmonary index has significant predictive value for RPH and a reduction in PASP after PEA. Lower values of the aortopulmonary index suggest a better outcome after PEA.

摘要

目的

本研究旨在回顾性评估使用计算机断层扫描肺动脉造影(CTPA)预测慢性血栓栓塞性肺动脉高压(CTEPH)患者肺动脉内膜剥脱术(PEA)后残余肺动脉高压(RPH)的情况。

方法

我们回顾性分析了2008年至2015年在本中心接受PEA的131例CTEPH患者的数据。术前测量了肺动脉和胸主动脉的多个直径。我们评估了这些测量值(及其指数)与通过超声心动图估计的肺动脉收缩压(PASP)所代表的RPH体征之间的关系。

结果

观察到主动脉肺动脉指数与PEA后1年任何残余高血压和中度/重度高血压的预测之间,以及PEA后2年任何残余高血压和重度高血压的预测之间存在显著相关性。主动脉肺动脉指数与术后1年PASP的降低显著相关。较低的主动脉肺动脉指数(升主动脉≤0.88,降主动脉≤0.64)预示着较低的RPH。

结论

术前CTPA参数可用于评估PEA后RPH的风险。主动脉肺动脉指数对RPH以及PEA后PASP的降低具有显著的预测价值。较低的主动脉肺动脉指数表明PEA后的预后较好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae25/8166393/1d613860565c/10.1177_03000605211002024-fig1.jpg

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