Frank Joachim, Kirchner Elisabeth, Padberg Frank, Huber Dorothea
IPU Internationale Psychoanalytische Universität Stromstraße 1 D-10555 Berlin Deutschland.
Klinik für Psychosomatische Medizin und Psychotherapie München Klinik Harlaching Deutschland.
Z Psychosom Med Psychother. 2021 Sep;67(3):256-270. doi: 10.13109/zptm.2021.67.oa6. Epub 2021 Mar 25.
In a naturalistic long-term follow-up design this study investigated the improvement of depressive symptom severity, mentalization deficiency and personality organization. 300 patients with depressive symptoms were assessed at three evaluation times (before therapy, after therapy and one to three years after discharge) with the Patient Health Questionnaire Depression Scale (PHQ-9), the Mentalization Questionnaire (MZQ) and the Inventory of Personality Organization (IPO-16). Patients improved significantly in depressive symptom severity with strong impact. Especially patients with severe depression symptoms improved in mentalization deficits and personality organization during and after inpatient treatment. Chronic depressive patients improved in mentalization rather than in personality organization. Depressive symptom severity correlates with mentalization deficits and structural impairment. Mentalization deficits differed depending on the severity of depression, as other studies already showed. The more severe depressive symptoms, the more likely mentalization deficits and structural impairment improved. However, the lack of control groups limits the causal proof of efficacy. Mentalization deficits and personality organization should be recorded timely in order to choose adequate technique.
在一项自然主义的长期随访设计中，本研究调查了抑郁症状严重程度、心理化缺陷和人格组织的改善情况。使用患者健康问卷抑郁量表（PHQ - 9）、心理化问卷（MZQ）和人格组织量表（IPO - 16），在三个评估时间点（治疗前、治疗后以及出院后一至三年）对300名有抑郁症状的患者进行了评估。患者的抑郁症状严重程度有显著改善，影响较大。尤其是重度抑郁症状患者在住院治疗期间及之后，心理化缺陷和人格组织方面有所改善。慢性抑郁患者在心理化方面有所改善，而非人格组织方面。抑郁症状严重程度与心理化缺陷和结构损伤相关。正如其他研究已经表明的，心理化缺陷因抑郁严重程度而异。抑郁症状越严重，心理化缺陷和结构损伤改善的可能性就越大。然而，缺乏对照组限制了疗效的因果证明。应及时记录心理化缺陷和人格组织情况，以便选择适当的技术。
