Urology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Urology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
BMJ Case Rep. 2021 Mar 24;14(3):e240593. doi: 10.1136/bcr-2020-240593.
Invasive urothelial carcinoma shows marked propensity for divergent differentiation. Several of these 'variant' morphologies have been described in literature and recognised in the 2004 WHO classification. In this report, we detail a case of bladder tumour, diagnosed to be a lipid-rich variant on histopathology after transurethral resection of bladder tumour. Our case encompasses the complete clinical spectrum of this rare and aggressive subtype of urothelial carcinoma starting from initial presentation to postoperative follow-up and recurrence. A keen eye for recognising these variants can ensure a timely diagnosis of these variant and administration of a therapy distinctive from that used in conventional invasive urothelial carcinoma.
浸润性尿路上皮癌表现出明显的多向分化倾向。其中一些“变异”形态已在文献中描述,并在 2004 年 WHO 分类中得到认可。在本报告中,我们详细描述了一例膀胱肿瘤病例,该病例在经尿道膀胱肿瘤切除术(TURBT)后,组织病理学诊断为富含脂质的变异型。我们的病例涵盖了这种罕见且侵袭性的尿路上皮癌亚型的完整临床谱,从初始表现到术后随访和复发。敏锐地识别这些变体可以确保及时诊断这些变体,并采用与传统浸润性尿路上皮癌不同的治疗方法。