手术部位感染与通过选择麻醉剂优化宿主免疫的围手术期处理。
Surgical Site Infections and Perioperative Optimization of Host Immunity by Selection of Anesthetics.
机构信息
Department of Anesthesiology, Perioperative and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Department of Anaesthesia, Harvard Medical School, USA.
出版信息
Biomed Res Int. 2021 Mar 8;2021:5576959. doi: 10.1155/2021/5576959. eCollection 2021.
Surgical site infections are significant health care issues, and efforts to mitigate their occurrence have been ongoing worldwide, mainly focusing to reduce the spillage of microbes to the otherwise sterile tissues. Optimization of host immunity has been also recognized including temperature regulation (normothermia), adequate oxygenation, and glucose management. A number of papers have described the role of anesthetics in host immunity. The role of anesthetics in postoperative outcomes including surgical site infections has been also studied. We will review the current literature and propose the importance of anesthetic selection to potentially mitigate surgical site infections.
手术部位感染是重大的医疗保健问题，全球范围内一直在努力减少其发生，主要集中在减少微生物对原本无菌组织的溢出。宿主免疫的优化也得到了认可，包括体温调节（正常体温）、充分的氧合和葡萄糖管理。许多论文描述了麻醉在宿主免疫中的作用。麻醉在术后结果（包括手术部位感染）中的作用也得到了研究。我们将回顾当前的文献，并提出选择麻醉剂的重要性，以潜在地减少手术部位感染。
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