[前列腺癌间质放疗中局部肿瘤控制的决定因素]
[Determinants of local tumor control in interstitial radiotherapy of prostatic cancer].
作者信息
Sommerkamp H, Rupprecht M, Bruggmoser G, Wannenmacher M
机构信息
Abteilung für Urologie, Klinikum der Universität Freiburg.
出版信息
Urologe A. 1988 Mar;27(2):117-22.
Clinical followup of 52 patients treated with I-125 implants for localized prostatic cancer demonstrated local control in 85% and failure in 15%. Determining factors for local control or failure were analyzed and underline that homogeneous dose distribution is the most important factor for local control in interstitial radiotherapy. With the use of I-125 seeds this can only be achieved in small-volume (T2) stages with refined technique. For larger tumor volumes (T3) an external boost or the use of other radionuclides is preferable.
对52例接受I - 125粒子植入治疗局限性前列腺癌的患者进行临床随访，结果显示局部控制率为85%，失败率为15%。分析了局部控制或失败的决定因素，强调均匀剂量分布是间质放疗中局部控制的最重要因素。使用I - 125粒子，只有在小体积（T2）阶段采用精细技术才能实现这一点。对于较大肿瘤体积（T3），采用外照射增敏或使用其他放射性核素更为可取。
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