Department of Gastroenterology, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
Department of Pathology, Robert J. Tomsich Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
Scand J Gastroenterol. 2021 May;56(5):624-628. doi: 10.1080/00365521.2021.1896774. Epub 2021 Mar 25.
Endoscopic eradication therapy (EET) with maximal acid suppression is the cornerstone for the management of patients with Barrett's esophagus (BE) associated dysplasia. The occurrence of buried dysplastic glands after re-epithelialization of a neo-squamous epithelium is of concern for endoscopists. Here, we present a patient with BE and high-grade dysplasia successfully treated by EET who developed buried dysplastic BE during surveillance. A review of literature on buried dysplasia after successful endoscopic therapy of BE is also discussed.
内镜下根除治疗(EET)联合最大胃酸抑制是 Barrett 食管(BE)相关异型增生患者管理的基石。新形成的鳞状上皮再上皮化后隐匿性异型腺体的出现一直是内镜医生关注的问题。本文报道了一例 BE 伴高级别异型增生患者经 EET 成功治疗后,在随访中发现隐匿性异型 BE。本文还对 BE 内镜治疗成功后隐匿性异型增生的文献进行了复习。