脊椎动物血浆中磷酸八钙的饱和度

Degree of saturation of blood plasma in vertebrates with octocalcium phosphate.

作者信息

Driessens F C, Verbeeck R M, van Dijk J W, Borggreven J M

机构信息

Department of Oral Biomaterials, Catholic University, Nijmegen, The Netherlands.

出版信息

Z Naturforsch C J Biosci. 1988 Jan-Feb;43(1-2):74-6. doi: 10.1515/znc-1988-1-215.

DOI:10.1515/znc-1988-1-215

PMID:3376518

Abstract

In previous papers it has been shown that octocalcium phospate OCP occurs in bone mineral of vertebrates. Although this compound is not stable, there is a continuous new-formation of OCP due to bone turnover. Literature data of the calcium and phosphate concentrations in the blood plasma of vertebrates were collected and the degree of saturation with OCP was calculated. The results show that blood plasma of vertebrates is almost saturated with OCP. This fact indicates that OCP is the solubility controlling phase in the mineral of vertebrates. Further it verifies the expectation based on physicochemical theory that the interaction between body fluids and bone mineral is important in the calcium and phosphate homeostasis.

摘要

在之前的论文中已经表明，八钙磷酸钙（OCP）存在于脊椎动物的骨矿物质中。尽管这种化合物不稳定，但由于骨转换，OCP会持续重新形成。收集了脊椎动物血浆中钙和磷酸盐浓度的文献数据，并计算了OCP的饱和度。结果表明，脊椎动物的血浆几乎被OCP饱和。这一事实表明，OCP是脊椎动物矿物质中控制溶解度的相。此外，它验证了基于物理化学理论的预期，即体液与骨矿物质之间的相互作用在钙和磷酸盐的稳态中很重要。