Taha Hesham Salah El Din, Shaker Mirna Mamdouh
Department of Cardiology, Faculty of Medicine, Cairo University, 27 Nafezet Sheem El Shafae St Kasr Al Ainy, Cairo, 11562, Egypt.
Egypt Heart J. 2021 Mar 25;73(1):30. doi: 10.1186/s43044-021-00158-5.
Myocardial reperfusion may cause profound electrophysiological alterations and can lead to serious reperfusion arrhythmias (RA). Management of RA and the accompanying electrical storm that may occur remains a problem. To our knowledge, the role of balloon re-inflation of the infarct-related artery (IRA) has never been addressed as a treatment modality for RA presenting as ventricular tachycardia (VT) with pulse or supraventricular tachycardia (SVT).
Six patients presenting with ST elevation myocardial infarction (STEMI) in the first 12 h, who underwent successful primary percutaneous coronary intervention (PCI), developed RA in the cathlab after restoration of flow in the IRA. The RA was in the form of VT with pulse, except in one patient who had SVT. In four patients, the RA was associated with hemodynamic instability. The mean age of the studied patients was 59.16 ± 7.94 years, and four were males. Coronary artery disease risk factors were prevalent, with four patients being hypertensive, two dyslipidemic, one diabetic, and 2 current smokers. One patient had a history of prior myocardial infarction (MI), and none had a history of congestive heart failure. The coronary angiography showed 100% occlusion of IRA in all patients and 2-3-vessel disease was present in 50%. PCI was successful with restoration of thrombolysis in myocardial infarction (TIMI) 2-3 flow in IRA in all cases. The mean time to revascularization from the onset of chest pain was 4.88 ± 2.68 h. In all cases, balloon re-inflation was successful in terminating the arrhythmias. None of the patients needed direct current cardioversion or anti-arrhythmic drugs for management of the acute arrhythmia.
Balloon re-inflation of IRA was successful in terminating RA that develop in the form of VT with pulse or SVT.
心肌再灌注可能会引起深刻的电生理改变,并可能导致严重的再灌注心律失常(RA)。RA及可能出现的伴随电风暴的处理仍然是一个问题。据我们所知,梗死相关动脉(IRA)球囊再扩张作为一种治疗呈脉搏性室性心动过速(VT)或室上性心动过速(SVT)的RA的治疗方式,其作用从未得到探讨。
6例在发病12小时内出现ST段抬高型心肌梗死(STEMI)且接受了成功的直接经皮冠状动脉介入治疗(PCI)患者,在IRA血流恢复后于导管室发生了RA。除1例为SVT外,RA均表现为脉搏性VT。4例患者的RA伴有血流动力学不稳定。研究患者的平均年龄为59.16±7.94岁,男性4例。冠状动脉疾病危险因素普遍存在,4例患者患有高血压,2例血脂异常,1例糖尿病患者,2例为现吸烟者。1例患者有既往心肌梗死(MI)病史,无充血性心力衰竭病史。冠状动脉造影显示所有患者IRA均为100%闭塞,50%存在2 - 3支血管病变。所有病例PCI均成功,IRA恢复心肌梗死溶栓(TIMI)2 - 3级血流。从胸痛发作到血管再通的平均时间为4.88±2.68小时。在所有病例中,球囊再扩张成功终止了心律失常。所有患者均无需直流电复律或抗心律失常药物来处理急性心律失常。
IRA球囊再扩张成功终止了以脉搏性VT或SVT形式出现的RA。