Department of Gastroenterology, Tallaght University Hospital, Dublin 24, Ireland.
School of Medicine, Trinity College Dublin, Dublin, Ireland.
Methods Mol Biol. 2021;2283:15-20. doi: 10.1007/978-1-0716-1302-3_2.
The concept of the urea breath test (UBT), as a method for H. pylori detection, is based on the ability of the H. pylori urease enzyme to break down an isotope-labelled urea solution ingested by the patient into carbon dioxide (CO) and ammonia. This chapter summarizes the current use of the UBT and the utility of the "UBT and Treat" strategy compared to other strategies for the management of H. pylori infection . Different UBT methods are described as well as factors affecting the accuracy of the test.
尿素呼气试验（UBT）作为一种检测 H. pylori 的方法，其原理是 H. pylori 脲酶能够将患者摄入的同位素标记尿素溶液分解为二氧化碳（CO）和氨。本章总结了 UBT 的当前应用以及与其他 H. pylori 感染管理策略相比，“UBT 与治疗”策略的效用。还描述了不同的 UBT 方法以及影响检测准确性的因素。
