Binda Cecilia, Dabizzi Emanuele, Sinagra Emanuele, Fornelli Adele, Saragoni Luca, Cennamo Vincenzo, Anderloni Andrea, Fabbri Carlo
Gastroenterology and Digestive Endoscopy Unit, Forlì - Cesena Hospitals, AUSL Romagna, Forlì-Cesena, Italy.
Gastroenterology and Interventional Endoscopy Unit, Ospedale Maggiore "C.A. Pizzardi", AUSL Bologna, Bologna, Italy.
Clin Endosc. 2021 Jul;54(4):613-617. doi: 10.5946/ce.2020.241. Epub 2021 Mar 25.
Peritoneal carcinomatosis (PC) is defined as a metastatic involvement of the peritoneum by several other primary sites and it is characterized by a marked worsening of prognosis, with limited treatment opportunities. Subsequently, PC should be ruled out before any invasive treatment is administered. A new through-the-needle micro-biopsy forceps (MF) was recently introduced that permits micro-histology cores. In this case series, we evaluated the feasibility of MF in the assessment of PC to complete patient diagnostic work-ups. Five consecutive patients referred for endoscopic ultrasound staging were sampled using MF. Sampling was feasible in all patients with a technical success of 100%. No adverse events were reported in any cases. This technique was feasible and safe with a technical success rate of 100%. It permitted sampling of peritoneal irregularity, obtained high-quality tissue fragments in all cases, and enabled an additional assessment, i.e., immunohistochemical staining.
腹膜癌病（PC）被定义为其他几个原发部位对腹膜的转移性侵犯，其特征是预后显著恶化，治疗机会有限。因此，在进行任何侵入性治疗之前，都应排除PC。最近推出了一种新型的经针微活检钳（MF），可获取微组织芯。在本病例系列中，我们评估了MF在PC评估中完成患者诊断检查的可行性。连续5例因内镜超声分期就诊的患者使用MF进行采样。所有患者的采样均可行，技术成功率为100%。所有病例均未报告不良事件。该技术可行且安全，技术成功率为100%。它允许对腹膜不规则处进行采样，在所有病例中均获得了高质量的组织碎片，并能够进行额外的评估，即免疫组化染色。
