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[视觉分析器预调谐及大脑激活对实验性神经症发展的影响]

[Effect of pretuning of the visual analyzer and activation of the brain on the development of experimental neuroses].

作者信息

Lavrov V V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Jan-Feb;38(1):153-61.

PMID:3376559
Abstract

It is shown that pretuning of analyzer system is a factor initiating a sharpening of the analysis and subsequent development of experimental neurosis resulting from excessively acute differentiation. A number of behavioural and electrophysiological characteristics was recorded in cats in norm and in neurotization. Pathological action was established of both artificially increased and lowered brain activation. The increase was reached by additional electrical stimulation of various cortical and subcortical brain structures. The lowering took place following isolation of the reticular formation from the visual system. In response to artificial increase of excitation in neuroticized animals seizures took place. The obtained facts confirm the suggestion that pathogenesis of neurosis is accompanied by disturbance of normal activity of activation-deactivation mechanism.

摘要

结果表明,分析器系统的预调谐是引发分析锐化以及随后因过度敏锐分化而导致实验性神经症发展的一个因素。记录了正常状态和神经化状态下猫的一些行为和电生理特征。证实了人为增加和降低大脑激活的病理作用。通过对大脑不同皮质和皮质下结构进行额外电刺激来实现增加。通过将网状结构与视觉系统隔离来实现降低。在神经化动物中,对人为增加的兴奋的反应会引发癫痫发作。所获得的事实证实了以下观点,即神经症的发病机制伴随着激活 - 失活机制正常活动的紊乱。

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Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Jan-Feb;38(1):153-61.
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Neurosci Behav Physiol. 1992 Jul-Aug;22(4):320-7. doi: 10.1007/BF01182874.