肠道功能低下会通过迷走神经传导导致大脑功能低下。 - Suppr

A depressed gut makes for a depressed brain via vagal transmission.

作者信息

Munshi Soumyabrata

机构信息

Tulane Brain Institute, Department of Cell and Molecular Biology, Tulane University, 6823 St. Charles Avenue, New Orleans, LA 70118, United States of America.

出版信息

Brain Behav Immun. 2021 Jul;95:15-16. doi: 10.1016/j.bbi.2021.03.017. Epub 2021 Mar 23.

DOI:10.1016/j.bbi.2021.03.017

PMID:33766699

Abstract

摘要

相似文献

A depressed gut makes for a depressed brain via vagal transmission.肠道功能低下会通过迷走神经传导导致大脑功能低下。

Brain Behav Immun. 2021 Jul;95:15-16. doi: 10.1016/j.bbi.2021.03.017. Epub 2021 Mar 23.

A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes.膈下迷走神经在抑郁样表型小鼠中的作用：来自具有抑郁样表型的 Chrna7 敲除小鼠的粪便微生物群移植后。

Brain Behav Immun. 2021 May;94:318-326. doi: 10.1016/j.bbi.2020.12.032. Epub 2021 Jan 8.

A role of gut-microbiota-brain axis via subdiaphragmatic vagus nerve in depression-like phenotypes in Chrna7 knock-out mice.肠道微生物群-脑轴通过膈下迷走神经在 Chrna7 敲除小鼠的抑郁表型中的作用。

Prog Neuropsychopharmacol Biol Psychiatry. 2023 Jan 10;120:110652. doi: 10.1016/j.pnpbp.2022.110652. Epub 2022 Sep 30.

Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve.摄入肠道乳杆菌和雷特氏乳杆菌通过迷走神经引起抗生素处理小鼠的抑郁和快感缺失样表型。

J Neuroinflammation. 2020 Aug 15;17(1):241. doi: 10.1186/s12974-020-01916-z.

Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain-gut-microbiota axis via the subdiaphragmatic vagus nerve.摄入 Faecalibaculum rodentium 会导致 Ephx2 基因敲除小鼠出现抑郁样表型：通过膈下迷走神经的脑-肠-微生物群轴发挥作用。

J Affect Disord. 2021 Sep 1;292:565-573. doi: 10.1016/j.jad.2021.06.006. Epub 2021 Jun 11.

Neuroinflammation through the vagus nerve-dependent gut-microbiota-brain axis in treatment-resistant depression.神经炎症通过迷走神经依赖性肠道微生物群-脑轴在治疗抵抗性抑郁症中的作用。

Prog Brain Res. 2023;278:61-77. doi: 10.1016/bs.pbr.2023.01.003. Epub 2023 Mar 2.

Effects of microbiota transplantation and the role of the vagus nerve in gut-brain axis in animals subjected to chronic mild stress.慢性轻度应激动物的肠道菌群移植及迷走神经在肠-脑轴中的作用。

J Affect Disord. 2020 Dec 1;277:410-416. doi: 10.1016/j.jad.2020.08.013. Epub 2020 Aug 14.

Intestinal microbiota impact sepsis associated encephalopathy via the vagus nerve.肠道微生物群通过迷走神经影响脓毒症相关性脑病。

Neurosci Lett. 2018 Jan 1;662:98-104. doi: 10.1016/j.neulet.2017.10.008. Epub 2017 Oct 6.

Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis.慢性不可预测轻度应激小鼠供体的粪便微生物群移植通过肠道微生物群-炎症-大脑轴影响受体小鼠的焦虑样和抑郁样行为。

Stress. 2019 Sep;22(5):592-602. doi: 10.1080/10253890.2019.1617267. Epub 2019 May 24.

A key role of the subdiaphragmatic vagus nerve in the depression-like phenotype and abnormal composition of gut microbiota in mice after lipopolysaccharide administration.膈下迷走神经在脂多糖给药后小鼠抑郁样表型和肠道微生物群落异常组成中的关键作用。

Transl Psychiatry. 2020 Jun 9;10(1):186. doi: 10.1038/s41398-020-00878-3.

引用本文的文献

Recognizing the role of the vagus nerve in depression from microbiota-gut brain axis.从微生物群-肠-脑轴认识迷走神经在抑郁症中的作用。

Front Neurol. 2022 Nov 10;13:1015175. doi: 10.3389/fneur.2022.1015175. eCollection 2022.

Therapeutic Implications of the Microbial Hypothesis of Mental Illness.精神疾病的微生物假说的治疗意义。

Curr Top Behav Neurosci. 2023;61:315-351. doi: 10.1007/7854_2022_368.

Impaired blood-brain barrier in the microbiota-gut-brain axis: Potential role of bipolar susceptibility gene TRANK1.微生物群-肠-脑轴中的血脑屏障损伤：双相易感性基因 TRANK1 的潜在作用。

J Cell Mol Med. 2021 Jul;25(14):6463-6469. doi: 10.1111/jcmm.16611. Epub 2021 May 20.

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A depressed gut makes for a depressed brain via vagal transmission.

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