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回肠造口术患者肠道对草酸的吸收

Intestinal absorption of oxalic acid in ileostomized patients.

作者信息

Duce A M, Jerez E, Rapado A, Cajigal R

机构信息

Department of Digestive Surgery, Fundación Jiménez Diaz, Clinica de la Concepción, Madrid, Spain.

出版信息

Acta Chir Scand. 1988 Apr;154(4):297-9.

PMID:3376690
Abstract

The diagnostic usefulness of an intestinal oxalic acid absorption test was evaluated in nine patients with ileostomy. They received an oral overload of 250 mg sodium oxalate and 4 Ci oxalic acid-C14 and a controlled diet. The urinary levels of cold and radioactive oxalic acid were measured 24 and 48 hours after the overload. Intestinal oxalic acid absorption in the ileostomized patients was found to be normal, with 16.13 +/- 5.1% of the administered dose being eliminated/recovered in the urine 48 hours after the overload (control value = 14.5 +/- 2.8%). The dose of radioactivity excreted on the second day after the overload was smaller in the ileostomy group than in the control group, possibly connected with the absence of colon. The results suggest that in ileostomized patients whose colon has been removed, oxalic acid absorption is normal. Hence there appears to be no risk of oxalic lithiasis in this group.

摘要

对9名回肠造口术患者进行了肠道草酸吸收试验的诊断效用评估。他们口服了250毫克草酸钠和4居里草酸-C14,并采用了控制饮食。在负荷后24小时和48小时测量尿液中冷草酸和放射性草酸的水平。发现回肠造口术患者的肠道草酸吸收正常,负荷后48小时尿液中排出/回收的给药剂量为16.13±5.1%(对照值=14.5±2.8%)。回肠造口术组负荷后第二天排出的放射性剂量低于对照组,这可能与结肠缺失有关。结果表明,在结肠已被切除的回肠造口术患者中,草酸吸收正常。因此,该组似乎不存在草酸结石的风险。

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