Sharma Reetika, Ambroise Marie Moses, Ramdas Anita, Ravichandran Kandasamy
Department of Pathology, Pondicherry Institute of Medical Sciences, Puducherry, India.
Department of Biostatistics, Pondicherry Institute of Medical Sciences, Puducherry, India.
J Midlife Health. 2020 Oct-Dec;11(4):231-235. doi: 10.4103/jmh.JMH_110_20. Epub 2021 Jan 21.
The objective of this study is to determine the clinical predictors of unsatisfactory Pap smears.
This was a case-control study done in a tertiary care institute. All unsatisfactory conventional pap (CP) smears between January 2015 and June 2017 were retrieved, and the slides were viewed. Clinical details were recorded from request forms and case files. Simple and multiple logistic regression analyses were used to identify the predictors of unsatisfactory CP smears.
In this study, we have included 314 unsatisfactory Pap smears and 541 controls with satisfactory Pap smears. Clinical parameters such as older age and cervical erosion proved to be important predictors of unsatisfactory pap smears. The most common reason for unsatisfactory pap smears was due to a paucity of epithelial elements (66.6%), followed by obscuration of smear details by blood/inflammatory cells/mucus (9.9%) and air drying artifacts (4.4%). There were multiple reasons in 19.1% of cases with unsatisfactory pap smears.
Our study shows that older age groups and cervical erosion are predictors of unsatisfactory pap smears. Incidence of unsatisfactory pap smears can be reduced by education and retraining of health-care workers and doctors.
本研究的目的是确定巴氏涂片结果不满意的临床预测因素。
这是一项在三级医疗机构开展的病例对照研究。检索了2015年1月至2017年6月期间所有不满意的传统巴氏（CP）涂片，并查看了玻片。从申请表和病例档案中记录临床细节。采用单因素和多因素逻辑回归分析来确定不满意CP涂片的预测因素。
在本研究中，我们纳入了314例巴氏涂片结果不满意的病例以及541例巴氏涂片结果满意的对照。年龄较大和宫颈糜烂等临床参数被证明是巴氏涂片结果不满意的重要预测因素。巴氏涂片结果不满意的最常见原因是上皮成分不足（66.6%），其次是血液/炎症细胞/黏液掩盖涂片细节（9.9%）和气干假象（4.4%）。19.1%的巴氏涂片结果不满意的病例存在多种原因。
我们的研究表明，年龄较大的人群和宫颈糜烂是巴氏涂片结果不满意的预测因素。通过对医护人员和医生进行教育和再培训，可以降低巴氏涂片结果不满意的发生率。
