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真空封闭引流联合精准超声引导清创术治疗非哺乳期乳腺炎的临床疗效评价

Clinical therapeutic evaluation of vacuum sealing drainage and precise ultrasound-guided debridement in the treatment of non-lactational mastitis.

作者信息

Chen Ruifu, Chen Junpeng, Peng Ajing, Yang Lihua, Zhou Ruijuan

机构信息

Department of Thoracic and Breast Surgery, Xiamen Hospital of Traditional Chinese Medicine, Xiamen, Fujian 361000, P.R. China.

出版信息

Exp Ther Med. 2021 May;21(5):480. doi: 10.3892/etm.2021.9911. Epub 2021 Mar 12.

DOI:10.3892/etm.2021.9911
PMID:33767775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7976372/
Abstract

The aim of the present study was to compare the efficacy of vacuum sealing drainage (VSD) and precise ultrasound-guided debridement in the treatment of non-lactational mastitis and to determine the optimal surgical treatment. A set of 60 cases diagnosed with non-lactational mastitis who had received surgical treatment at the Department of Thoracic and Breast Surgery of Xiamen Hospital of Traditional Chinese Medicine (Xiamen, China) between July 2017 and June 2019 were included. According to the surgical method, 30 patients were assigned to the VSD group and 30 patients were assigned to the precise ultrasound-guided debridement group. The clinicopathological data of the two groups were compared. The overall rates of recurrence and new incidence were 6.8 and 8.5%, respectively. The mean total disease course was 5.3 months and all of the patients were cured after treatment. Except for the hospitalization time and postoperative pain scores, the clinicopathological data between the two groups were similar. The hospitalization time in the VSD group was significantly longer than that in the precise ultrasound-guided debridement group. Pain scores on the first and third days after the operation in the precise ultrasound-guided debridement group were significantly higher than those in the VSD group (P=0.008 and 0.001, respectively). In conclusion, the efficacies of VSD and precise ultrasound-guided debridement for the treatment of non-lactational mastitis were generally both satisfactory without significant differences. Of note, the former is suitable for patients with inverted nipples and obvious skin ulcerations, while the latter is mainly suitable for patients with abscesses, small surgical incisions and those who require short hospital stays.

摘要

本研究旨在比较封闭式负压引流(VSD)与精准超声引导清创术治疗非哺乳期乳腺炎的疗效,并确定最佳手术治疗方案。纳入了2017年7月至2019年6月期间在厦门市中医院(中国厦门)胸外科及乳腺外科接受手术治疗的60例非哺乳期乳腺炎患者。根据手术方法,将30例患者分配至VSD组,30例患者分配至精准超声引导清创组。比较两组的临床病理数据。复发率和新发率分别为6.8%和8.5%。平均总病程为5.3个月,所有患者治疗后均治愈。除住院时间和术后疼痛评分外,两组的临床病理数据相似。VSD组的住院时间明显长于精准超声引导清创组。精准超声引导清创组术后第1天和第3天的疼痛评分明显高于VSD组(分别为P = 0.008和0.001)。总之,VSD和精准超声引导清创术治疗非哺乳期乳腺炎的疗效总体上均令人满意,无显著差异。值得注意的是,前者适用于乳头内陷和皮肤溃疡明显的患者,而后者主要适用于有脓肿、手术切口小及需要短期住院的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e30/7976372/7f15a50b0546/etm-21-05-09911-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e30/7976372/54d2c396e0f9/etm-21-05-09911-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e30/7976372/7f15a50b0546/etm-21-05-09911-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e30/7976372/54d2c396e0f9/etm-21-05-09911-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e30/7976372/7f15a50b0546/etm-21-05-09911-g01.jpg

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Different Treatments for Granulomatous Lobular Mastitis: A Systematic Review and Meta-Analysis.肉芽肿性小叶性乳腺炎的不同治疗方法:一项系统评价和荟萃分析
Breast Care (Basel). 2020 Feb;15(1):60-66. doi: 10.1159/000501498. Epub 2019 Jul 10.
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Minimally invasive comprehensive treatment for granulomatous lobular mastitis.
肉芽肿性小叶性乳腺炎的微创综合治疗
BMC Surg. 2020 Feb 22;20(1):34. doi: 10.1186/s12893-020-00696-w.
4
Clinicopathological features of granulomatous lobular mastitis and mammary duct ectasia.肉芽肿性小叶性乳腺炎和乳腺导管扩张症的临床病理特征
Oncol Lett. 2020 Jan;19(1):840-848. doi: 10.3892/ol.2019.11156. Epub 2019 Nov 28.
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Granulomatous mastitis: etiology, imaging, pathology, treatment, and clinical findings.肉芽肿性乳腺炎:病因、影像学表现、病理学、治疗和临床表现。
Breast Cancer Res Treat. 2018 Oct;171(3):527-534. doi: 10.1007/s10549-018-4870-3. Epub 2018 Jul 3.
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