视神经乳头浆细胞瘤作为多发性骨髓瘤的一种表现形式。
Optic nerve head plasmacytoma as a manifestation of multiple myeloma.
作者信息
Sandor Kaitlin P, Micieli Jonathan A, Peragallo Jason H
机构信息
Department of Ophthalmology, Emory University, Atlanta, GA, USA.
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.
出版信息
Taiwan J Ophthalmol. 2021 Feb 10;11(1):97-100. doi: 10.4103/tjo.tjo_81_20. eCollection 2021 Jan-Mar.
Extramedullary disease in multiple myeloma is uncommon and associated with a poorer prognosis. Extramedullary disease involving the orbit is even more unusual, with optic nerve involvement being rare. We describe an optic nerve head plasmacytoma in a 45-year-old female in the setting of systemic relapsed, refractory IgA kappa multiple myeloma. The case highlights the importance of keeping extramedullary disease spread in the differential for vision loss in a patient with a history of multiple myeloma. In addition, it describes an unusual location for presentation of extramedullary disease, the optic nerve head, which has rarely been described.
多发性骨髓瘤的髓外病变并不常见，且预后较差。累及眼眶的髓外病变更为罕见，视神经受累则极为罕见。我们报告一例45岁女性患者，在系统性复发、难治性IgA κ型多发性骨髓瘤背景下出现视神经乳头浆细胞瘤。该病例凸显了在有骨髓瘤病史的患者中，将髓外病变扩散纳入视力丧失鉴别诊断的重要性。此外，它描述了髓外病变的一个不寻常的发病部位——视神经乳头，此前鲜有报道。
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