Ramalho Sara Almeida, Abecasis Francisca, Santos Letícia, Leite Vanessa, Gonçalves Diogo, Pintassilgo Inês, Broa Ana Luisa
Internal Medicine Department, Hospital Garcia de Orta, Almada, Portugal.
Pathology Department, Hospital Garcia de Orta, Almada, Portugal.
Eur J Case Rep Intern Med. 2021 Feb 25;8(3):002360. doi: 10.12890/2021_002360. eCollection 2021.
Hypercalcaemia is a frequent finding in malignancies including lymphomas. However, there are no reports of hypercalcaemia in hepatosplenic T-cell lymphoma (HSTCL). HSTCL is a rare and aggressive neoplasm which is usually difficult to diagnose. We present a case of HSTCL in which hypercalcaemia was the initial presentation.
Hepatosplenic T-cell lymphoma (HSTCL) is difficult to diagnose, has a poor prognosis and usually presents with hepatosplenomegaly, B symptoms and cytopenias.Hypercalcaemia is an extremely rare clinical presentation of HSTCL.Severe hypercalcaemia is a life-threatening condition and should always be corrected and investigated.
高钙血症在包括淋巴瘤在内的恶性肿瘤中很常见。然而，尚无肝脾T细胞淋巴瘤（HSTCL）伴高钙血症的报道。HSTCL是一种罕见且侵袭性强的肿瘤，通常难以诊断。我们报告一例以高钙血症为首发表现的HSTCL病例。
肝脾T细胞淋巴瘤（HSTCL）难以诊断，预后不良，通常表现为肝脾肿大、B症状和血细胞减少。高钙血症是HSTCL极为罕见的临床表现。严重高钙血症是一种危及生命的情况，应始终予以纠正并进行检查。
