妊娠期首诊获得性血栓性血小板减少性紫癜，经血浆置换和利妥昔单抗治疗后预后良好：一例报告
Acquired thrombotic thrombocytopenic Purpura diagnosed during first trimester of pregnancy with excellent outcome after plasma exchange and rituximab, a case report.
作者信息
Arzuaga-Mendez Javier, Moreno Maite, Mateos-Mazón Juan J, Vara Miriam, Dueñas Marta, Del Orbe Rafael A, Amutio Elena, Arrizabalaga Beatriz, García-Ruiz Juan C
机构信息
Hematology and Hemotherapy Service Cruces University Hospital Biocruces Bizkaia Health Research Institute Barakaldo Bizkaia Spain.
出版信息
Clin Case Rep. 2021 Feb 2;9(3):1304-1306. doi: 10.1002/ccr3.3752. eCollection 2021 Mar.
Abstract
Acquired thrombotic thrombocytopenic purpura is a life-threatening condition that rarely presents during pregnancy. Early diagnosis and treatment with plasma exchange is needed to achieve a good pregnancy outcome.
摘要
获得性血栓性血小板减少性紫癜是一种危及生命的疾病，在孕期很少出现。需要早期诊断并进行血浆置换治疗，以获得良好的妊娠结局。
相似文献
1
Acquired thrombotic thrombocytopenic Purpura diagnosed during first trimester of pregnancy with excellent outcome after plasma exchange and rituximab, a case report.妊娠期首诊获得性血栓性血小板减少性紫癜，经血浆置换和利妥昔单抗治疗后预后良好：一例报告
Clin Case Rep. 2021 Feb 2;9(3):1304-1306. doi: 10.1002/ccr3.3752. eCollection 2021 Mar.
2
Post-Partum Thrombotic Thrombocytopenic Purpura (TTP) in a Patient with known Idiopathic (Immune) Thrombocytopenic Purpura: a case report and review of the literature.一名已知患有特发性（免疫性）血小板减少性紫癜的患者发生产后血栓性血小板减少性紫癜：病例报告及文献综述
J Med Case Rep. 2018 Jun 1;12(1):147. doi: 10.1186/s13256-018-1692-1.
3
Acquired Thrombotic Thrombocytopenic Purpura Without Anti-ADAMTS13 Antibody Caused by Influenza A (H1N1) Virus Successfully Treated by Plasma Exchange: A Case Report.获得性血栓性血小板减少性紫癜无抗 ADAMTS13 抗体由甲型流感病毒 (H1N1) 成功治疗血浆置换：一例报告。
Am J Case Rep. 2021 Aug 2;22:e932251. doi: 10.12659/AJCR.932251.
4
A case of severe ADAMTS13 deficiency presenting as thrombotic thrombocytopenic purpura in pregnancy.一例以妊娠期血栓性血小板减少性紫癜为表现的严重ADAMTS13缺乏症病例。
Med Pregl. 2012 Sep-Oct;65(9-10):436-9. doi: 10.2298/mpns1210436n.
5
Pregnancy-associated thrombotic thrombocytopenic purpura complicated by Sjögren's syndrome and non-neutralising antibodies to ADAMTS13: a case report.妊娠相关性血栓性血小板减少性紫癜合并干燥综合征及抗 ADAMTS13 非中和抗体：病例报告。
BMC Pregnancy Childbirth. 2021 Dec 3;21(1):804. doi: 10.1186/s12884-021-04167-9.
6
[Thrombotic thrombocytopenic purpura during pregnancy refractory to plasma exchange and rituximab].[妊娠期间难治性血栓性血小板减少性紫癜：血浆置换和利妥昔单抗治疗无效]
Rinsho Ketsueki. 2019;60(3):209-212. doi: 10.11406/rinketsu.60.209.
7
Active Hepatitis C Leading to Refractory Thrombotic Thrombocytopenic Purpura - A Dubious Association and The Challenges Faced in Management.活动性丙型肝炎导致难治性血栓性血小板减少性紫癜——一种可疑的关联及管理中面临的挑战
Cureus. 2019 Jul 16;11(7):e5147. doi: 10.7759/cureus.5147.
8
Rituximab for acute plasma-refractory thrombotic thrombocytopenic purpura: A case report.利妥昔单抗治疗急性血浆难治性血栓性血小板减少性紫癜：一例报告
Ann Med Surg (Lond). 2022 Sep 28;82:104789. doi: 10.1016/j.amsu.2022.104789. eCollection 2022 Oct.
9
Child-onset and adolescent-onset acquired thrombotic thrombocytopenic purpura with severe ADAMTS13 deficiency: a cohort study of the French national registry for thrombotic microangiopathy.儿童期和青少年期起病的获得性血栓性血小板减少性紫癜伴严重ADAMTS13缺乏症：法国全国血栓性微血管病登记处的一项队列研究
Lancet Haematol. 2016 Nov;3(11):e537-e546. doi: 10.1016/S2352-3026(16)30125-9. Epub 2016 Oct 3.
10
Successful treatment of plasma exchange-refractory thrombotic thrombocytopenic purpura with rituximab: A case report.利妥昔单抗成功治疗血浆置换难治性血栓性血小板减少性紫癜：一例报告。
World J Clin Cases. 2020 Jun 26;8(12):2617-2622. doi: 10.12998/wjcc.v8.i12.2617.
引用本文的文献
1
An Interesting Case of Refractory Thrombotic Thrombocytopenic Purpura in the First Trimester of a Twin Pregnancy.双胎妊娠孕早期难治性血栓性血小板减少性紫癜1例
Cureus. 2023 Oct 16;15(10):e47153. doi: 10.7759/cureus.47153. eCollection 2023 Oct.
2
Rituximab in the treatment of immune-mediated thrombotic thrombocytopenic purpura.利妥昔单抗治疗免疫介导的血栓性血小板减少性紫癜
Blood Transfus. 2023 Sep;21(5):369-374. doi: 10.2450/BloodTransfus.503. Epub 2023 Mar 17.
本文引用的文献
1
Thrombotic thrombocytopenic purpura during pregnancy versus imitator of preeclampsia.妊娠期血栓性血小板减少性紫癜与子痫前期的模仿者
Transfusion. 2015 Oct;55(10):2516-8. doi: 10.1111/trf.13207. Epub 2015 Aug 10.
2
Thrombotic thrombocytopenic purpura and pregnancy: presentation, management, and subsequent pregnancy outcomes.血栓性血小板减少性紫癜与妊娠：临床表现、处理方法及后续妊娠结局。
Blood. 2014 Jul 10;124(2):211-9. doi: 10.1182/blood-2014-02-553131. Epub 2014 May 23.
3
Guidelines on the use of therapeutic apheresis in clinical practice-evidence-based approach from the Writing Committee of the American Society for Apheresis: the sixth special issue.美国血液分离协会写作委员会制定的临床实践中治疗性血液分离术使用指南：循证方法，第六期特刊。
J Clin Apher. 2013 Jul;28(3):145-284. doi: 10.1002/jca.21276.
4
Rituximab for thrombotic thrombocytopenic purpura: benefit of early administration during acute episodes and use of prophylaxis to prevent relapse.利妥昔单抗治疗血栓性血小板减少性紫癜：急性发作期早期给药的益处和预防复发的应用。
J Thromb Haemost. 2013 Mar;11(3):481-90. doi: 10.1111/jth.12114.
5
Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies.血栓性血小板减少性紫癜及其他血栓性微血管病的诊断与管理指南
Br J Haematol. 2012 Aug;158(3):323-35. doi: 10.1111/j.1365-2141.2012.09167.x. Epub 2012 May 25.
6
A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura.一项评估利妥昔单抗联合血浆置换治疗急性获得性血栓性血小板减少性紫癜的安全性和有效性的 2 期研究。
Blood. 2011 Aug 18;118(7):1746-53. doi: 10.1182/blood-2011-03-341131. Epub 2011 Jun 2.
7
Pregnancy outcomes after maternal exposure to rituximab.母亲接触利妥昔单抗后的妊娠结局。
Blood. 2011 Feb 3;117(5):1499-506. doi: 10.1182/blood-2010-07-295444. Epub 2010 Nov 23.
8
Efficacy and safety of rituximab in adult patients with idiopathic relapsing or refractory thrombotic thrombocytopenic purpura: results of a Spanish multicenter study.利妥昔单抗治疗成人特发性复发或难治性血栓性血小板减少性紫癜的疗效和安全性：一项西班牙多中心研究的结果
Transfus Apher Sci. 2010 Dec;43(3):299-303. doi: 10.1016/j.transci.2010.09.018. Epub 2010 Oct 12.
9
Thrombotic thrombocytopenic purpura in the first trimester and successful pregnancy.孕早期血栓性血小板减少性紫癜与成功妊娠
Ann Hematol. 2009 Mar;88(3):287-9. doi: 10.1007/s00277-008-0579-4. Epub 2008 Aug 7.
10
Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family.人血管性血友病因子裂解蛋白酶的纯化及其作为金属蛋白酶家族新成员的鉴定。
Blood. 2001 Sep 15;98(6):1662-6. doi: 10.1182/blood.v98.6.1662.
Zotero 插件