Rabinowitsch J J, Barinowa M W, Kaufman O J, Glagolewa W W
Z Exp Chir. 1977;10(5):259-68.
The authors examined the surfactant in canine lungs at autotransplantation by assessing the alveolar stability values after preparation according to the method of Pattle. Moreover, microscopic and ultrastructural examinations were performed. The stability value of the normal lung was found to be 0.84 +/- 0.031. No essential change occurred after immediate lung transplantation and at delayed autotransplantation with preservation up to 24 hours. Alveolar stability values were not lowered after lung preservation up to 2, resp. 24, hours at +4 degrees C. The acute dystelectasis by preservation for 2 or 24 hours had no effect on the surfactant. At longer preservation (48, 72, or 96 hours) the stability values of the alveoles decreased, suggesting a decrease of surfactant. Electron microscopy revealed decreased density of osmiophilic bodies 24 hours after lung preservation.
作者通过按照帕特尔方法制备后评估肺泡稳定性值，研究了自体移植犬肺中的表面活性剂。此外，还进行了显微镜和超微结构检查。发现正常肺的稳定性值为0.84±0.031。即刻肺移植后以及延迟自体移植且保存长达24小时后，未发生本质变化。在4℃下保存2小时或24小时后，肺的肺泡稳定性值并未降低。保存2小时或24小时导致的急性肺不张对表面活性剂没有影响。在更长时间的保存（48、72或96小时）后，肺泡的稳定性值下降，提示表面活性剂减少。电子显微镜显示肺保存24小时后嗜锇小体密度降低。
