Ribeiro E Ribeiro Renan, Lewin Eleanor R, Hart Jesse L, Quddus Mohammad Ruhul, Hansen Katrine
Int J Gynecol Pathol. 2022 Jan 1;41(1):82-85. doi: 10.1097/PGP.0000000000000777.
Extrauterine Mullerian adenosarcomas (MA) are rare and often associated with endometriosis. We report a 55-yr-old patient seen in consultation for abdominal pain and bloating. Imaging was suggestive of a left adnexal mass and "peritoneal carcinomatosis". Pathological examination of the specimen revealed a MA arising in the left fallopian tube, with sarcomatous overgrowth, diffuse peritoneal involvement and omental "caking". Next-generation sequencing identified a MEIS1-NCOA2 gene fusion, previously unreported in MA.
子宫外苗勒管腺肉瘤（MA）罕见，且常与子宫内膜异位症相关。我们报告一例55岁因腹痛和腹胀前来会诊的患者。影像学检查提示左侧附件包块和“腹膜癌病”。标本的病理检查显示左侧输卵管发生了MA，伴有肉瘤样过度生长、弥漫性腹膜受累和网膜“饼状粘连”。二代测序鉴定出一种MEIS1-NCOA2基因融合，此前在MA中未报道过。
