Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi 110029, India.
Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi 110029, India.
J Gynecol Obstet Hum Reprod. 2021 Sep;50(7):102132. doi: 10.1016/j.jogoh.2021.102132. Epub 2021 Mar 26.
Adenomyosis associated abnormal uterine bleeding (AUB-A) often remains non-responsive to medical management. Uterine sparing treatment in young patients presenting with refractory AUB-A poses a challenge.
A 28-years-old woman presenting with AUB-A with failed medical therapy did not improve with uterine artery embolization (UAE). She underwent a second session of UAE with smaller embolic particles to which she responded. The reported case is interesting as patient conceived spontaneously despite transiently diminished post-UAE ovarian reserves, indicating spontaneous recovery of ovarian function.
UAE is a promising option for young patients, though UAE for adenomyosis may require smaller embolic particles to be effective which may diminish ovarian reserves due to non-target effects, however recovery is possible in young patients..
腺肌病相关异常子宫出血(AUB-A)常对药物治疗无反应。对于有难治性 AUB-A 的年轻患者,保留子宫的治疗方法是一个挑战。
一位 28 岁的女性因 AUB-A 就诊,药物治疗失败,子宫动脉栓塞术(UAE)也没有改善。她接受了第二次 UAE 治疗,使用了更小的栓塞颗粒,这对她有效。该病例很有趣,因为尽管 UAE 治疗后卵巢储备短暂减少,但患者仍自然受孕,表明卵巢功能自发恢复。
UAE 是年轻患者的一种有前途的选择,尽管 UAE 治疗腺肌病可能需要更小的栓塞颗粒才能有效,这可能会由于非靶向作用而减少卵巢储备,但在年轻患者中是有可能恢复的。