Weber Sebastian M, Hilt Gerhard
Fachbereich Chemie, Philipps-Universität Marburg, Marburg, Germany.
Institut für Chemie, Carl Von Ossietzky Universität Oldenburg, Oldenburg, Germany.
Front Chem. 2021 Mar 11;9:635826. doi: 10.3389/fchem.2021.635826. eCollection 2021.
This review will outline the recent advances in chemo-, regio-, and stereoselective (cross-) dimerization of terminal alkynes to generate 1,3-enynes using different types of iron and cobalt catalysts with altering oxidation states of the active species. In general, the used ligands have a crucial effect on the stereoselectivity of the reaction; e.g., bidentate phosphine ligands in cobalt catalysts can generate the -configured dimerization product, while tridentate phosphine ligands can generate either the -configured dimerization product or the branched isomer. Furthermore, the hydroalkynylation of silyl-substituted acetylenes as donors to internal alkynes as acceptors will be discussed using cobalt and nickel catalysts.
本综述将概述使用不同类型、具有不同氧化态活性物种的铁和钴催化剂，使末端炔烃进行化学、区域和立体选择性（交叉）二聚以生成1,3-烯炔的最新进展。一般来说，所使用的配体对反应的立体选择性有至关重要的影响；例如，钴催化剂中的双齿膦配体可生成构型的二聚产物，而三齿膦配体可生成构型的二聚产物或支链异构体。此外，还将讨论使用钴和镍催化剂，使硅基取代乙炔作为供体与内炔作为受体进行氢烷氧基化反应。
