Song Zi-Liang, Wu Shao-Hui, Zhang Dao-Liang, Jiang Wei-Feng, Qin Mu, Liu Xu
Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Front Cardiovasc Med. 2021 Mar 10;8:630090. doi: 10.3389/fcvm.2021.630090. eCollection 2021.
To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke. A total of 116 symptomatic, drug-refractory AF patients with a history of stroke, and 1:2 matched patients without a history of stroke were enrolled. Of these, 28 cases occurred stroke within 3 months (Group 1), 88 cases with stroke history longer than 3 months (Group 2), and 232 cases without stroke (Group 3). PVI was performed in all patients, extended to ablation of linear lesions ablation. The periprocedural stroke rates and other procedure-related in-hospital complications did not differ significantly among the three groups. The maintenance rate of SR after the procedure showed no significant difference ( = 0.333), 52.7, 66.4, and 70.7% in Group 1, 2, and 3, respectively. Furthermore, the comparison between a history of stroke and those without it were also shown no significant difference ( = 0.351). Radiofrequency ablation for AF patients occurred stroke, even within 3 months is safe and effective, without higher periprocedural complication rate and recurrence rate.
评估射频导管消融术对有卒中病史的心房颤动患者的临床安全性和有效性。共纳入116例有卒中病史的症状性、药物难治性房颤患者，以及按1:2匹配的无卒中病史患者。其中，28例在3个月内发生卒中（第1组），88例卒中病史超过3个月（第2组），232例无卒中（第3组）。所有患者均行肺静脉隔离术，并扩展至线性病变消融。三组围手术期卒中发生率及其他与手术相关的院内并发症无显著差异。术后窦性心律维持率无显著差异（=0.333），第1、2、3组分别为52.7%、66.4%和70.7%。此外，有卒中病史者与无卒中病史者之间的比较也无显著差异（=0.351）。对有卒中病史的房颤患者进行射频消融术，即使在3个月内也是安全有效的，围手术期并发症发生率和复发率不会更高。
