Wan Libin, Gao Huoliang, Yan Ge, Gao Haidong, Chen Mantang
Institute of Business Scientific, Henan Academy of Sciences, Wenhua Road #87, Zhengzhou, Henan 450003, China.
Zhengzhou Tobacco Research Institute of CNTC, Fengyang Street #2, Zhengzhou, Henan 450001, China.
ACS Omega. 2021 Mar 11;6(11):7478-7486. doi: 10.1021/acsomega.0c06000. eCollection 2021 Mar 23.
Molecularly imprinted polymers (MIPs) with high specific recognition capability are promising in environmental remediation. However, traditional MIPs usually show poor specific binding affinity toward templates in pure aqueous medium, thus greatly limiting their practical applications in wastewater treatment. Herein, we proposed a facile and versatile method to synthesize a water-compatible hierarchically porous MIP (HP-MIP), in which a metal-organic gel (MOG) was formed by in situ assembly and acted as a removable structural modulator. Remarkably, the integration of the MOG modulator and template imprinting defects significantly improved the specific template binding affinity of HP-MIP in water. The adsorption behavior of HP-MIP fitted well with the heterogeneous Freundlich isotherm, suggesting that HP-MIP possessed greater site heterogeneity to sildenafil than HP-NIP, which confirmed the efficiency of HP-MIP for the removal of sildenafil from water. This approach provides an important pathway to prepare water-compatible porous MIP for efficient removal of highly toxic organic pollutants from wastewater.
具有高特异性识别能力的分子印迹聚合物（MIP）在环境修复方面具有广阔前景。然而，传统的MIP在纯水性介质中通常对模板表现出较差的特异性结合亲和力，从而极大地限制了它们在废水处理中的实际应用。在此，我们提出了一种简便通用的方法来合成一种水相容性分级多孔MIP（HP-MIP），其中通过原位组装形成金属有机凝胶（MOG）并作为可去除的结构调节剂。值得注意的是，MOG调节剂与模板印迹缺陷的整合显著提高了HP-MIP在水中对模板的特异性结合亲和力。HP-MIP的吸附行为与非均相Freundlich等温线拟合良好，表明HP-MIP对西地那非具有比HP-NIP更大的位点非均质性，这证实了HP-MIP从水中去除西地那非的效率。该方法为制备水相容性多孔MIP以有效去除废水中的高毒性有机污染物提供了一条重要途径。
