Maggiore Paul, Anastasius Malcolm, Huang Alex L, Blanke Philipp, Leipsic Jonathon
Centre for Heart Valve Innovation, St Paul's Hospital, University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6.
Radiol Cardiothorac Imaging. 2020 Feb 13;2(1):e190106. doi: 10.1148/ryct.2020190106. eCollection 2020 Feb.
The mitral valve is a complex structure with a three-dimensional saddle shape annulus. Mitral regurgitation occurs from leaflet coaptation failure that is either primary (a problem with the leaflets) or secondary (chamber dilatation in the setting of cardiomyopathy). There has been an increase in focus on transcatheter mitral valve interventions, for both mitral repair and replacement. These technologies have rapidly developed to provide treatment for a substantial number of patients with severe symptomatic mitral regurgitation who are at too high of a risk to undergo open heart surgery. CT assessment of the mitral valve has developed with equal rapidity, with regard to preprocedural planning for transcatheter therapies. This review will provide an overview of mitral valve anatomy, an update on the current transcatheter repair and replacement therapies, as well as a focused overview of the role of multislice CT in mitral assessment prior to intervention. © RSNA, 2020.
二尖瓣是一个具有三维鞍形瓣环的复杂结构。二尖瓣反流源于瓣叶对合失败,这种失败要么是原发性的(瓣叶问题),要么是继发性的(心肌病背景下的心室扩张)。经导管二尖瓣干预(包括二尖瓣修复和置换)受到的关注日益增加。这些技术迅速发展,为大量有严重症状性二尖瓣反流且接受心脏直视手术风险过高的患者提供了治疗方法。关于经导管治疗的术前规划,二尖瓣的CT评估也同样迅速发展。本综述将概述二尖瓣解剖结构,介绍当前经导管修复和置换治疗的最新情况,并重点概述多层CT在干预前二尖瓣评估中的作用。©RSNA,2020年。