Lacher D A, Paolino M J
Department of Pathology, Medical College of Ohio, Toledo 43699.
Clin Chem. 1988 Jun;34(6):1099-102.
Discriminant analysis of chemistry and hematology laboratory test results was used to classify patients with and without myocardial infarction in a coronary care unit. We studied 64 patients with myocardial infarction and 70 patients without infarction, using logistic regression, linear and quadratic discriminant analyses on untransformed and logarithmically transformed data. Serum aspartate aminotransferase (AST, EC 2.6.1.1), the best single discriminating test, classified 73% of patients correctly. Quadratic discriminant analysis on log-transformed data had a 98.5% classification accuracy when all variables were used in the discriminant function and had the highest classification accuracy and precision. All of the discriminant methods had acceptable cross-validation.
运用化学和血液学实验室检测结果的判别分析，对冠心病监护病房中患有和未患心肌梗死的患者进行分类。我们研究了64例心肌梗死患者和70例非梗死患者，对未转换数据和对数转换数据进行逻辑回归、线性和二次判别分析。血清天冬氨酸氨基转移酶（AST，EC 2.6.1.1）是最佳的单一判别检测指标，能正确分类73%的患者。当判别函数中使用所有变量时，对数转换数据的二次判别分析分类准确率为98.5%，且具有最高的分类准确率和精度。所有判别方法的交叉验证均可接受。
