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病例报告:1例新型冠状病毒肺炎上呼吸道感染后腹膜结核患者发生粟粒性肺结核

Case Report: Development of Miliary Pulmonary Tuberculosis in a Patient with Peritoneal Tuberculosis after COVID-19 Upper Respiratory Tract Infection.

作者信息

Elziny Moustafa M, Ghazy Ahmed, Elfert Khaled A, Aboukamar Mohamed

机构信息

1Department of Family Medicine, Hamad Medical Corporation, Doha, Qatar.

2Department of Bariatric Medicine, Hamad Medical Corporation, Doha, Qatar.

出版信息

Am J Trop Med Hyg. 2021 Mar 30;104(5):1792-1795. doi: 10.4269/ajtmh.20-1156.

Abstract

We report a 29-year-old patient who presented with coronavirus disease 2019 (COVID-19) upper respiratory tract infection in addition to clinical, laboratory, and radiological findings highly suggestive of peritoneal tuberculosis (TB) without pulmonary involvement. Two weeks after the resolution of COVID-19 infection, he presented with shortness of breath and oxygen desaturation requiring intubation and admission to the intensive care unit. The workup confirmed miliary pulmonary TB. The patient subsequently improved on antitubercular treatment. We discuss the possible contribution of COVID-19 infection to the rapid progression of TB infection to involve the lung in a miliary pattern, and how the coexistence of the two diseases might have led to a worse outcome.

摘要

我们报告了一名29岁的患者,该患者除了有临床、实验室和影像学检查结果高度提示为腹膜结核(TB)且无肺部受累外,还出现了2019冠状病毒病(COVID-19)上呼吸道感染。COVID-19感染消退两周后,他出现呼吸急促和氧饱和度下降,需要插管并入住重症监护病房。检查确诊为粟粒性肺结核。该患者随后在抗结核治疗后病情好转。我们讨论了COVID-19感染对结核感染迅速进展至粟粒样累及肺部的可能作用,以及这两种疾病的共存可能如何导致更差的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfc4/8103485/3ef336d668f5/tpmd201156f1.jpg

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