University of Utah Health Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Salt Lake City, Utah, USA.
Division of Anesthesia, Critical Care and Pain, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
Int J Obstet Anesth. 2021 May;46:102975. doi: 10.1016/j.ijoa.2021.102975. Epub 2021 Mar 11.
Placenta accreta spectrum (PAS) is a leading contributor to major obstetric hemorrhage and severe maternal morbidity in the developed world. In the United States, PAS has become the most common cause of peripartum hysterectomy. Over the last 40 years, clinicians have also witnessed a dramatic increase in the incidence of PAS. In the 1950s, the incidence of PAS was reported to be 0.03 per 1000 pregnancies. Recent epidemiological studies estimate that the PAS incidence is between 0.79 and 3.11 in 1000 pregnancies. As a consequence, obstetric anesthesiologists are increasingly likely to be called upon to manage women with suspected PAS for delivery. Given the increasing incidence and the morbidity burden associated with PAS, anesthesiologists play a vital role in optimizing maternal outcomes for women with PAS. This review will provide up-to-date information on nomenclature, pathophysiology, risk factors, antenatal detection, systemic preparations (includes timing of delivery, location of surgery, pre-operative evaluation and patient positioning), surgical and anesthetic approach, intra-operative management, invasive radiology and postoperative plans.
胎盘部位滋养细胞肿瘤(PAS)是发达国家导致产后大出血和严重产妇发病率的主要原因之一。在美国,PAS 已成为围产期子宫切除术最常见的原因。在过去的 40 年里,临床医生也见证了 PAS 发病率的显著增加。在 20 世纪 50 年代,PAS 的发病率报道为每 1000 例妊娠中 0.03 例。最近的流行病学研究估计,PAS 的发病率在每 1000 例妊娠中为 0.79 至 3.11 例。因此,产科麻醉师越来越有可能被要求为疑似 PAS 的妇女分娩提供管理。鉴于 PAS 的发病率不断上升和与 PAS 相关的发病率负担,麻醉师在优化 PAS 妇女的母婴结局方面发挥着至关重要的作用。这篇综述将提供关于 PAS 的最新信息,包括命名法、病理生理学、危险因素、产前检测、全身准备(包括分娩时机、手术地点、术前评估和患者体位)、手术和麻醉方法、术中管理、介入放射学和术后计划。