Suppr超能文献

瑞士严重哮喘的诊断和管理:对专家和全科医生进行的调查结果分析。

Diagnosis and Management of Severe Asthma in Switzerland: Analysis of Survey Results Conducted with Specialists and General Practitioners.

机构信息

Service d'Immunologie et d'Allergologie, Hôpitaux Universitaires de Genève, Geneva, Switzerland.

Novartis Pharma Schweiz AG, Rotkreuz, Switzerland.

出版信息

Respiration. 2021;100(6):476-487. doi: 10.1159/000514628. Epub 2021 Mar 30.

Abstract

BACKGROUND

Severe asthma commonly affects 5-10% of the asthmatic population and accounts for approximately 50% of the overall asthma costs.

OBJECTIVE

This analysis investigated how severe asthma is diagnosed, treated, and managed by specialists and general practitioners (GPs) in Switzerland.

METHODS

Two surveys, one each among specialists (N = 44) and GPs (N = 153), were conducted to understand their self-perception on diagnosis, treatment, and management of severe asthma.

RESULTS

Fifty-five percent of the specialists felt very confident and 43% confident in recognizing the symptoms of severe asthma and diagnosing severe asthma. In contrast, 9% of the GPs were very confident and 59% confident in diagnosing severe asthma. More specific diagnostic tests for severe asthma, like total and specific immunoglobulin E levels and measurement of the fraction of exhaled nitric oxide, were run by specialists (χ2 = 171.4; df = 15, p < 0.001). GPs and specialists were using different measurements to assess severe asthma (χ2 = 385.2; df = 13, p < 0.001) and their prescribing patterns differed significantly (χ2 = 189.8; df = 10, p < 0.001). GPs referred patients with severe asthma if the diagnosis was unclear (24%), if treatment failure occurred (26%), and if the patients were at high risk (41%).

CONCLUSIONS

Oral corticosteroids (OCSs) are considered as background therapy for severe asthma by GPs and specialists. In order to reduce the OCS burden, there is a need to improve the awareness for other add-on therapies. A joint collaboration between GPs and specialists is the key to leverage therapeutic strategies together.

摘要

背景

重度哮喘通常影响哮喘患者的 5-10%,占哮喘总费用的约 50%。

目的

本分析研究了瑞士的专家和全科医生(GP)如何诊断、治疗和管理重度哮喘。

方法

对专家(N=44)和 GP(N=153)进行了两项调查,以了解他们对重度哮喘的诊断、治疗和管理的自我认知。

结果

55%的专家对识别重度哮喘的症状和诊断重度哮喘非常有信心,而 43%的专家有信心。相比之下,9%的 GP 对诊断重度哮喘非常有信心,而 59%的 GP 有信心。更具体的重度哮喘诊断测试,如总免疫球蛋白 E 和特异性免疫球蛋白 E 水平以及呼出气一氧化氮分数的测量,由专家进行(χ2=171.4;df=15,p<0.001)。GP 和专家使用不同的测量方法来评估重度哮喘(χ2=385.2;df=13,p<0.001),他们的处方模式也有显著差异(χ2=189.8;df=10,p<0.001)。GP 将转诊重度哮喘患者,包括诊断不明确(24%)、治疗失败(26%)和患者处于高风险(41%)。

结论

口服皮质类固醇(OCS)被 GP 和专家视为重度哮喘的基础治疗。为了减少 OCS 的负担,需要提高对其他附加治疗的认识。GP 和专家之间的合作是共同利用治疗策略的关键。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验