Whiteley Mark S, Taylor Laura K, King Julie C, Hughes Brittany E
The Whiteley Clinic, Guildford, UK.
Faculty of Health and Biomedical Sciences, University of Surrey, Guildford, UK.
SAGE Open Med Case Rep. 2021 Mar 9;9:2050313X211000866. doi: 10.1177/2050313X211000866. eCollection 2021.
A 48-year-old woman attended to discuss a dilemma. She had suffered a cardiac arrest immediately following microsclerotherapy of leg telangiectasia with 0.3% aethoxysklerol. She had successful defibrillation and been transferred to hospital. In hospital, despite normal cardiac tests, she was diagnosed as having idiopathic cardiac arrest. The exposure to aethoxysklerol was discounted by her cardiologists as a cause of her arrest. Following the hospital protocol, she was strongly advised to have an implantable defibrillator. Cardiac arrest and myocardial infarction are documented after aethoxysklerol injection with proposed mechanisms being anaphylaxis, direct cardiotoxicity or endothelin-1 release. Before consenting to an implantable defibrillator, which may have its own complications in the long term, doctors and the patient need to be certain that this arrest was not due to a reaction to aethoxysklerol.
一名48岁女性前来讨论一个两难问题。她在接受0.3%乙氧硬化醇治疗腿部毛细血管扩张症后立即发生心脏骤停。她成功接受了除颤并被送往医院。在医院里，尽管心脏检查结果正常，但她仍被诊断为特发性心脏骤停。她的心脏病专家排除了乙氧硬化醇暴露是导致她心脏骤停的原因。按照医院的诊疗方案，她被强烈建议植入植入式除颤器。有文献记载，注射乙氧硬化醇后会发生心脏骤停和心肌梗死，推测其机制为过敏反应、直接心脏毒性或内皮素-1释放。在同意植入可能长期存在自身并发症的植入式除颤器之前，医生和患者需要确定此次心脏骤停并非由对乙氧硬化醇的反应所致。
