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唇腭裂患者术前及术后听力评估——一项前瞻性研究。

Pre-operative and post-operative audiological assessment in cleft lip and palate patients-a prospective study.

作者信息

Acharya Priyanka, Sahana B A, Desai Anil, Jalisatgi Roshan R, Kumar Niranjan

机构信息

SDM Craniofacial and Research Centre, SDM College of Dental Sciences and Hospital, Sattur, Dharwad, 580009, Karnataka, India.

Oral and Maxillofacial Surgery, SDM Craniofacial and Research Centre, SDM College of Dental Sciences and Hospital, Sattur, Dharwad, 580009, Karnataka, India.

出版信息

J Oral Biol Craniofac Res. 2021 Apr-Jun;11(2):321-329. doi: 10.1016/j.jobcr.2021.03.003. Epub 2021 Mar 17.

DOI:10.1016/j.jobcr.2021.03.003
PMID:33786295
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7994542/
Abstract

PURPOSE

To assess association of audiological defects in cleft lip and palate (CLP) following two stage cheiloplasty and palatoplasty using clinical evaluation and otoscopy and effect of the surgical repair at an interval of one year.

MATERIALS AND METHODS

A pilot research study was performed on sixty CLP patients of 1-6 years of age reporting at Craniofacial & Research Centre, Dharwad, India between October 2016 to October 2018.Subjects were assessed based on history, clinical examination and otoscopy for audiometric defects including Serous otitis media (SOM), retraction pockets, impacted wax pre-palatoplasty and findings were compared with control group. Study group were followed up postoperatively at 1, 3, 6 and 12 months and statistical analysis was carried.

RESULTS

Higher incidence of conductive audiological defects were noted in study group (96.6%) to control group (8.33%). Of the sixty cleft patients subjected to screening otoscopy, 58 subjects had significant findings like serous otitis media(12.07%), retraction pockets(23.14%), impacted wax(62.04%), bulging of tympanic membrane(3.45%) which were clinically unnoticed. Post palatoplasty no changes were noted at 1 and 3 months, however at 6- and 12months significant improvement was noted (55.17%), with three subjects lost to follow up (6.90%) and none presenting with permanent deafness.results.

CONCLUSION

Cleft anomalies occur in different degrees of severity and configuration with greater incidence of conductive hearing defects of 97%. Positive correlation was noted in cleft palate cases with significant improvement after palatoplasty at an earlier age. However, future long term studies are warranted for long term assessment of Eustachian tube function.conclusion.

摘要

目的

通过临床评估和耳镜检查,评估两期唇裂修复术和腭裂修复术后唇腭裂(CLP)患者的听力缺陷关联,以及一年间隔期手术修复的效果。

材料与方法

2016年10月至2018年10月期间,对印度达尔瓦德颅面研究中心报告的60例1 - 6岁CLP患者进行了一项初步研究。根据病史、临床检查和耳镜检查对受试者进行听力缺陷评估,包括浆液性中耳炎(SOM)、回缩袋、腭裂修复术前的耵聍堵塞,并将结果与对照组进行比较。研究组在术后1、3、6和12个月进行随访,并进行统计分析。

结果

研究组(96.6%)的传导性听力缺陷发生率高于对照组(8.33%)。在接受筛查耳镜检查的60例腭裂患者中,58例有明显发现,如浆液性中耳炎(12.07%)、回缩袋(23.14%)、耵聍堵塞(62.04%)、鼓膜膨出(3.45%),这些在临床上未被注意到。腭裂修复术后1个月和3个月未发现变化,但在6个月和12个月时观察到显著改善(55.17%),3例受试者失访(6.90%),无永久性耳聋病例。

结论

腭裂畸形的严重程度和形态各不相同,传导性听力缺陷的发生率较高,为97%。腭裂病例与早期腭裂修复术后的显著改善呈正相关。然而,需要未来的长期研究来对咽鼓管功能进行长期评估。

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J Oral Maxillofac Surg. 2019 Feb;77(2):405.e1-405.e15. doi: 10.1016/j.joms.2018.09.027. Epub 2018 Sep 29.
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Otologic Concerns for Cleft Lip and Palate Patient.唇腭裂患者的耳科问题
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Grommets for otitis media with effusion in children with cleft palate: a systematic review.腭裂患儿中耳积液的鼓膜切开置管术:一项系统评价
Pediatrics. 2014 Nov;134(5):983-94. doi: 10.1542/peds.2014-0323. Epub 2014 Oct 6.
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The incidence of secretory otitis media in cases of cleft palate.腭裂病例中分泌性中耳炎的发病率。
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Clinical study of otological manifestations in cases of cleft palate.腭裂病例中耳部表现的临床研究
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Evaluation of an auditory assessment protocol for Chinese infants with nonsyndromic cleft lip and/or palate.对非综合征性唇腭裂中国婴儿听觉评估方案的评估。
Cleft Palate Craniofac J. 2012 Sep;49(5):566-73. doi: 10.1597/09-140.1.
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Is otitis media with effusion almost always accompanying cleft palate in children?: the experience of 319 Asian patients.分泌性中耳炎是否几乎总是伴随腭裂患儿出现?:319 例亚洲患者的经验。
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