艾滋病相关肺孢子菌肺炎与艾滋病相关播散性组织胞浆菌病的血（1->3）-β-D-葡聚糖水平比较。
Comparison of Blood (1->3)-β-d-Glucan Levels in AIDS-Related Pneumocystis jirovecii Pneumonia and AIDS-Related Progressive Disseminated Histoplasmosis.
机构信息
Division of Infectious Diseases and Department of Internal Medicine, University of Arkansas for Medical Sciences and the Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA.
2Division of Infectious Diseases and Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
出版信息
Clin Infect Dis. 2021 Sep 15;73(6):1100-1102. doi: 10.1093/cid/ciab277.
In this retrospective study, (1->3)-β-d-glucan (B-glucan) was an unreliable marker for AIDS-related Pneumocystis jirovecii pneumonia (PCP) because a high percentage of participants with progressive disseminated histoplasmosis and respiratory symptoms had a positive B-glucan result. Where histoplasmosis is common, attributing B-glucan positivity to PCP without further testing risks misdiagnosis.
在这项回顾性研究中，(1->3)-β-d-葡聚糖（B-葡聚糖）作为艾滋病相关卡氏肺孢子菌肺炎（PCP）的标志物并不可靠，因为患有进行性播散组织胞浆菌病和呼吸道症状的患者中有很大一部分 B-葡聚糖检测结果呈阳性。在组织胞浆菌病较为常见的地区，如果不进行进一步检测，将 B-葡聚糖阳性归因于 PCP，可能会导致误诊。
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