American University of Beirut- Medical Center, Riad-El Solh st. 1107 2020, PO Box 11-0236, Beirut, Lebanon.
King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Pediatr Cardiol. 2021 Jun;42(5):1111-1118. doi: 10.1007/s00246-021-02588-z. Epub 2021 Mar 31.
Three-dimensional echocardiography is being used to evaluate left ventricular dimensions and ejection fraction in clinical practice. The validity and normal values have been established in a large group of normal adults, children and neonates. The aim of this study was to compare left ventricular dimensions and ejection fraction obtained from the same 3-dimensional echocardiography datasets using 2 commercially available applications: Philips QLAB and Tomtec 4D LEFT VENTRICLE-ANALYSIS. Fifty consecutive newborns or neonates coming to their first newborn visit within the first 3 weeks of live, were recruited. 38 babies underwent full Echocardiographic evaluation, including the acquisition of several 3-dimensional datasets, while naturally sleeping. Left ventricular dimensions, volumes and ejection fraction were measured using Philips QLAB version 9.0 and results were compared to results of the same datasets, analysed using TomTec 4D LV software. Mean left ventricular diastolic, and systolic volumes indexed to body surface area and ejection fraction were: 24.7 ± 3.6 ml/m, 9.2 ± 1.3 ml/m and 62 ± 3.8% using TomTec and 26.6 ± 3.8 ml/m, 10.4 ± 2 ml/m and 63 ± 3.1% using QLAB, respectively. Mean indexed left ventricular diastolic, and systolic volumes measured with QLAB were significantly higher as compared to TomTec with insignificant difference in the ejection fraction. Normal left ventricular indices obtained from 3-dimensional echocardiography datasets were established, using Philips QLAB and TomTec 4D LV ANALYSIS software. Measurements obtained were significantly different between those venders, and hence, may not be used interchangeably.
三维超声心动图用于评估临床实践中的左心室尺寸和射血分数。已在大量正常成年人、儿童和新生儿中建立了该方法的有效性和正常值。本研究旨在比较使用两种商业可用应用程序（Philips QLAB 和 Tomtec 4D LEFT VENTRICLE-ANALYSIS）从同一 3 维超声心动图数据集获得的左心室尺寸和射血分数。共招募了 50 名连续的新生儿或生后前 3 周内首次新生儿就诊的新生儿。38 名婴儿在自然睡眠时接受了完整的超声心动图评估，包括采集多个 3 维数据集。使用 Philips QLAB 版本 9.0 测量左心室尺寸、容积和射血分数，并将结果与使用 TomTec 4D LV 软件分析的相同数据集的结果进行比较。使用 TomTec 时，左心室舒张末期和收缩末期容积指数（以体表面积为单位）和射血分数分别为：24.7±3.6 ml/m2、9.2±1.3 ml/m2 和 62±3.8%，使用 QLAB 时分别为：26.6±3.8 ml/m2、10.4±2 ml/m2 和 63±3.1%。与 TomTec 相比，QLAB 测量的 indexed 左心室舒张末期和收缩末期容积明显更高，而射血分数差异无统计学意义。使用 Philips QLAB 和 TomTec 4D LV ANALYSIS 软件建立了正常的左心室指数。这两种供应商之间的测量值存在显著差异，因此不能互换使用。
