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由于颈椎病变导致的肌萎缩侧索硬化症(ALS)模仿症:从常见的压迫性脊髓病到罕见的脑脊液硬膜外聚集

ALS Mimics due to Affection of the Cervical Spine: From Common Compressive Myelopathy to Rare CSF Epidural Collection.

作者信息

Storti Benedetta, Diamanti Susanna, Tremolizzo Lucio, Riva Nilo, Lunetta Christian, Filippi Massimo, Ferrarese Carlo, Appollonio Ildebrando

机构信息

Neurology Unit, San Gerardo Hospital, and School of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.

Neuropathology Unit, "San Raffaele" Scientific Institute, Milan, Italy.

出版信息

Case Rep Neurol. 2021 Mar 4;13(1):145-156. doi: 10.1159/000512810. eCollection 2021 Jan-Apr.

Abstract

Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous disease, with chameleon presentations and several mimics. Considering the poor prognosis of ALS, their precise and timely identification is pivotal. Affection of the cervical spine represents one potential source of ALS mimics that should never be missed, since it is potentially treatable. We hereby present 5 cases initially diagnosed as ALS but eventually found to have different kinds of cervical spine affection, from a common compressive myelopathy to a rare space-occupying cystic fluid collection.

摘要

肌萎缩侧索硬化症(ALS)是一种临床异质性疾病,表现多样且有多种模仿疾病。鉴于ALS预后不佳,准确及时地识别这些疾病至关重要。颈椎病变是ALS模仿疾病的一个潜在来源,绝不能被忽视,因为它有可能得到治疗。我们在此报告5例最初被诊断为ALS,但最终发现患有不同类型颈椎病变的病例,从常见的压迫性脊髓病到罕见的占位性囊性积液。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4ad/7989791/92a88bb64eba/crn-0013-0145-g01.jpg

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