Patil M K, Subbaraj K
Department of Applied Mechanics, Indian Institute of Technology, Madras.
J Biomech. 1988;21(3):219-33. doi: 10.1016/0021-9290(88)90173-x.
The purpose of the investigation reported in this paper is to determine theoretically the fluid dynamic field in models of common iliac arterial bifurcation and to identify the flow features which might influence the predominant occurrence of atherosclerotic lesions at such sites. This has been accomplished by numerically simulating fluid flow through 90 degrees symmetric bifurcations with branch-to-trunk area ratios of 0.8-1.414 and for Reynolds numbers ranging from 100 to 400. The analysis predicts flow reversal along the outer wall in models with area ratios over unity for high Reynolds number range, while no flow reversal occurred in models with area ratio below unity; a low shear zone along the outer wall and high shear stresses at the divider lip. Adverse pressure gradients are observed along the outer wall downstream of the corner point, the magnitudes increased with Reynolds number for a given branch to area ratio. Biological implication of the results is discussed with specific reference to the sites of atherosclerotic lesions found in man for these geometries.
本文所报告的研究目的是从理论上确定髂总动脉分叉模型中的流体动力学场，并识别可能影响此类部位动脉粥样硬化病变主要发生情况的血流特征。通过对分支与主干面积比为0.8 - 1.414且雷诺数范围为100至400的90度对称分叉处的流体流动进行数值模拟，实现了这一目标。分析预测，在高雷诺数范围内，面积比大于1的模型中，沿外壁会出现逆流，而面积比小于1的模型中则不会出现逆流；沿外壁存在低剪切区，在分流唇处存在高剪切应力。在拐角点下游的外壁沿线观察到不利的压力梯度，对于给定的分支与面积比，其大小随雷诺数增加而增大。结合人体中这些几何形状部位发现的动脉粥样硬化病变部位，对结果的生物学意义进行了讨论。
