一名急性起病的强迫症女童的谷氨酸脱羧酶65抗体（抗GAD 65）与肺炎支原体抗体诊断难题
A Diagnostic Dilemma of Antiglutamic Acid Decarboxylase 65 (Anti-GAD 65) and Mycoplasma Pneumoniae Antibodies in a Girl Presenting with Acute-Onset Obsessive-Compulsive Disorder.
作者信息
Freeman Cecilia G, Langeveldt Antanoid J, Miller Robyn R
机构信息
Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.
Department of Pediatrics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE, USA.
出版信息
Case Rep Psychiatry. 2021 Mar 19;2021:6672028. doi: 10.1155/2021/6672028. eCollection 2021.
Abstract
Acute-onset obsessive-compulsive disorder can be challenging, especially when triggered by an underlying disease process. Clinicians often turn to Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS), but it is important to consider a broad differential in these patients. We present a case of a 9-year-old girl with acute-onset obsessive-compulsive behavior likely triggered by a post-infectious phenomenon that ultimately resolved following treatment with plasmapheresis.
摘要
急性起病的强迫症可能具有挑战性，尤其是由潜在疾病过程引发时。临床医生常常会想到与链球菌感染相关的儿科自身免疫性神经精神障碍（PANDAS），但对这些患者进行广泛的鉴别诊断很重要。我们报告一例9岁女孩，其急性起病的强迫行为可能由感染后现象引发，最终经血浆置换治疗后症状缓解。
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