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治疗 COVID-19:当前和潜在药物疗法综述。

Treatment of COVID-19: a review of current and prospective pharmacotherapies.

机构信息

Department of General Medicine, Barnet Hospital, Royal Free London NHS Foundation Trust, London, UK.

Department of Rheumatology and General Medicine, Barnet Hospital, Royal Free London NHS Foundation Trust, London, UK.

出版信息

Br J Hosp Med (Lond). 2021 Mar 2;82(3):1-9. doi: 10.12968/hmed.2021.0112. Epub 2021 Mar 12.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and have grave health and socioeconomic consequences worldwide. Researchers have raced to understand the pathophysiological mechanisms underpinning the disease caused by SARS-CoV-2 so that effective therapeutic targets can be discovered. This review summarises the key pharmacotherapies that are being investigated for treatment of COVID-19, including antiviral, immunomodulator and anticoagulation strategies.

摘要

由严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)引起的 2019 年冠状病毒病(COVID-19)大流行继续在全球范围内传播,并造成严重的健康和社会经济后果。研究人员竞相了解 SARS-CoV-2 引起的疾病的病理生理机制,以便发现有效的治疗靶点。这篇综述总结了正在研究用于治疗 COVID-19 的关键药物疗法,包括抗病毒、免疫调节剂和抗凝策略。

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