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自行使用抗生素的行为:斯里兰卡的一项全国性横断面调查。

Self-medication Behavior with antibiotics: a national cross-sectional survey in Sri Lanka.

机构信息

, The University of Sydney School of Pharmacy, Faculty of Medicine and Health, NSW, Australia.

Central Clinical School, Faculty of Medicine and Health, The University of Sydney, NSW, Australia.

出版信息

Expert Rev Anti Infect Ther. 2021 Oct;19(10):1341-1352. doi: 10.1080/14787210.2021.1911647. Epub 2021 Apr 14.

Abstract

BACKGROUND

Antibiotic self-medication is common in low- and middle-income countries. This study aimed to evaluate the Sri Lankan public's knowledge about and attitudes toward antibiotic use and self-medication, and factors associated with self-medication.

METHODS

A national cross-sectional, interviewer-administered, survey of a random household sample (N = 1100) was conducted. Factor analysis of the attitudinal items was conducted to investigate the factors associated with antibiotic self-medication.

RESULTS

A response rate of ninety-one percent (n = 998) responded. Knowledge about antibiotics was poor (mean = 12.5; SD = 3.5; (scale 0-27)). Half had previously used an antibiotic once in the past three months. About 11% (108/998) had self-medicated the last time they took antibiotics; mostly obtained from a pharmacy (82%; 89/108). Three attitudinal factors were obtained, explaining 56.1% of the variance. Respondents were less likely to self-medicate if they did not support (< 0.001) and (= 0.001); supported (= 0.003); and had greater for antibiotics (= 0.004).

CONCLUSION

There is limited knowledge about, and a high rate of self-medication with antibiotics.Factors contributing to self-medication could be addressed with appropriate public education campaigns, and policy changes.

摘要

背景

抗生素自我用药在中低收入国家很常见。本研究旨在评估斯里兰卡公众对抗生素使用和自我用药的知识和态度,以及与自我用药相关的因素。

方法

采用全国性的、由访谈员进行的、随机家庭样本(N=1100)的横断面调查。对态度项目进行因子分析,以调查与抗生素自我用药相关的因素。

结果

91%(n=998)的人做出了回应。对抗生素的了解很差(平均=12.5;标准差=3.5;(0-27 分))。一半的人在过去三个月中曾经服用过一次抗生素。大约 11%(108/998)的人在上一次服用抗生素时进行了自我用药;大部分是从药店购买的(82%;89/108)。得到了三个态度因素,解释了 56.1%的方差。如果受访者不支持(<0.001)和(=0.001);支持(=0.003);以及对抗生素的看法(=0.004),他们就不太可能自我用药。

结论

对,抗生素的了解有限,而且自我用药的比率很高。可以通过适当的公众教育运动和政策改变来解决导致自我用药的因素。

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