Pangalos C
Diagnostic Genetic Center, Athènes.
J Genet Hum. 1988 Jan;36(1-2):21-31.
The genetic counseling given at carriers of equilibrated chromosomal inversions is in relation with the type of the inversion. The risk for carriers of pericentric inversions concerning euchromatic regions depends on many factors, i.e. the length of the inserted segment in relation with the total length of the chromosome involved, the sex of the carrier and the way of assortment. In contrast, the carriers of pericentric inversions concerning the heterochromatic regions, as well as of paracentric inversions, have not a particular risk for their descendance.
对平衡染色体倒位携带者进行的遗传咨询与倒位类型有关。涉及常染色质区域的臂间倒位携带者的风险取决于许多因素,即插入片段的长度与所涉及染色体总长度的关系、携带者的性别以及分离方式。相比之下,涉及异染色质区域的臂间倒位携带者以及臂内倒位携带者,其后代没有特殊风险。