Division of Pulmonary Diseases and Critical Care Medicine, and.
Division of Pulmonary, Allergy, and Critical Care Medicine, Departmet of Medicine, Duke University, Durham, North Carolina.
Ann Am Thorac Soc. 2021 Nov;18(11):1868-1875. doi: 10.1513/AnnalsATS.202010-1300OC.
Surrogate decision-makers of patients with chronic critical illness (CCI) are at high risk for symptoms of post-traumatic stress disorder (PTSD). Whether patient health status after hospital discharge is a risk factor for surrogate PTSD symptoms is not known. To determine the association between patient health status 90 days after the onset of CCI and surrogate symptoms of PTSD. We performed a secondary analysis of the data from a multicenter randomized trial of a communication intervention for adult patients with CCI and their surrogate decision-makers. Surrogate PTSD symptoms were measured at 90 days using the Impact of Events Scale-Revised. For patients who were alive at 90 days, location was used as a marker of health status and included the following categories: ) home (relatively good health and low acuity), ) acute rehabilitation (moderate care needs and impairments, generally expected to improve), ) skilled nursing facility (moderate care needs and impairments, generally not expected to improve significantly or quickly), ) long-term acute care facility (persistently high acute care needs and functional impairment), and ) readmission to an acute care hospital (suggesting the highest acuity of illness and care needs of the cohort). Patients who died before 90 days were categorized as deceased. In the analyses, 365 surrogates and 256 patients were included. Among patients, 49% were female, and the mean age was 59 years. Among surrogates, 71% were female, and the mean age was 51 years. A directed acyclic graph was constructed to identify covariates to be included in the model. Compared with symptoms seen among surrogates of patients living at home, heightened PTSD symptoms were seen among surrogates of patients who were readmitted to an acute care hospital (β coefficient, 15.9; 95% confidence interval [CI], 4.5 to 27.3) or had died (β coefficient, 14.8; 95% CI, 8.8 to 20.9) at 90 days. Surrogates of patients with CCI who have died or have been readmitted to an acute care hospital at 90 days experience increased PTSD symptoms as compared with surrogates of patients who are living at home. These patients and surrogates represent a readily identifiable group who may benefit from enhanced emotional support.
慢性危重病(CCI)患者的替代决策人患创伤后应激障碍(PTSD)的症状风险很高。患者出院后健康状况是否是替代 PTSD 症状的危险因素尚不清楚。本研究旨在确定 CCI 发病后 90 天患者健康状况与替代 PTSD 症状之间的关系。我们对一项多中心、随机试验中关于成人 CCI 患者及其替代决策人沟通干预的数据分析进行了二次分析。90 天时使用修订后的事件影响量表(Impact of Events Scale-Revised)来测量替代 PTSD 症状。对于 90 天时仍存活的患者,根据其位置来作为健康状况的标志物,包括以下类别:)家庭(相对较好的健康状况和低疾病严重程度)、)急性康复(中等护理需求和功能障碍,一般预期会改善)、)熟练护理机构(中等护理需求和功能障碍,一般不会显著或快速改善)、)长期急性护理机构(持续高急性护理需求和功能障碍),以及)重新入住急性护理医院(提示该队列中疾病和护理需求的严重程度最高)。90 天前死亡的患者被归类为死亡。在分析中,纳入了 365 名替代决策人和 256 名患者。患者中,49%为女性,平均年龄为 59 岁。替代决策人中,71%为女性,平均年龄为 51 岁。构建有向无环图来确定要纳入模型的协变量。与家中存活患者的替代决策人相比,重新入住急性护理医院(β系数,15.9;95%置信区间[CI],4.5 至 27.3)或死亡(β系数,14.8;95% CI,8.8 至 20.9)的患者的替代决策人 PTSD 症状更明显。90 天内死亡或重新入住急性护理医院的 CCI 患者的替代决策人比家中存活的患者的 PTSD 症状更严重。这些患者和替代决策人代表了一个易于识别的群体,他们可能受益于增强情感支持。