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丹麦归因于首次肥胖相关心血管合并症的社会成本。

Attributable societal costs of first-incident obesity-related cardiovascular comorbidities in Denmark.

机构信息

VIVE, Danish Center for Social Science Research, Copenhagen, Denmark.

Novo Nordisk Denmark A/S, Copenhagen S, Denmark.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2021 Aug;21(4):673-681. doi: 10.1080/14737167.2021.1908130. Epub 2021 Apr 2.

DOI:10.1080/14737167.2021.1908130
PMID:33794723
Abstract

: Obesity is associated with increased societal costs, primarily due to its comorbidities. The objective of this study was to estimate the 3-year attributable societal costs of the first event of cardiovascular comorbidities among people with obesity.: We used an incidence-based cohort study based on Danish national registries. Attributable costs of each event were calculated as the difference between costs of individuals with an event and costs incurred by matched controls.: We identified 58,597 individuals with a diagnosis of obesity. On average, 2,038 individuals were diagnosed annually with one or more than ten cardiovascular comorbidities between 2007 and 2013. The 3-year attributable societal costs (health-care costs plus productivity loss) for patients of working age ranged from 8,164 EUR for other ischemic heart disease to 32,203 EUR for hemorrhagic stroke. In the incidence year, costs were mainly driven by health-care costs, while productivity loss and income transfer payments were the primary drivers in subsequent years.: The onset of obesity-related cardiovascular comorbidities affected health-care costs and work ability to an extent where sick pay and disability pension were required. Our study demonstrates the need to intensify obesity and cardiovascular disease risk factor management to prevent costly and debilitating obesity-related comorbidities.

摘要

肥胖与社会成本增加有关,主要是由于其合并症。本研究的目的是估算肥胖人群首次发生心血管合并症的 3 年归因于社会的成本。我们使用基于丹麦国家登记处的基于发病率的队列研究。每个事件的归因成本计算为有事件的个体的成本与匹配对照者发生的成本之间的差异。我们确定了 58597 名肥胖症诊断患者。平均而言,2007 年至 2013 年间,每年有 2038 名患者被诊断出患有一种或十种以上心血管合并症。对于工作年龄的患者,3 年归因于社会的(医疗保健成本加上生产力损失)成本范围从其他缺血性心脏病的 8164 欧元到出血性中风的 32203 欧元。在发病年度,成本主要由医疗保健成本驱动,而在随后的年份中,生产力损失和收入转移支付是主要驱动因素。肥胖相关心血管合并症的发作在一定程度上影响了医疗保健成本和工作能力,导致需要病假工资和残疾养恤金。我们的研究表明,需要加强肥胖和心血管疾病危险因素管理,以预防昂贵和使人衰弱的肥胖相关合并症。

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