Department of Orthodontics, Bauru Dental School, University of São Paulo, Bauru, Brazil.
Department of Orthodontics, Bauru Dental School, University of São Paulo, Bauru, Brazil.
Am J Orthod Dentofacial Orthop. 2021 Jun;159(6):714-723.e1. doi: 10.1016/j.ajodo.2020.11.036. Epub 2021 Mar 30.
This single-center, 2-arm, parallel-group randomized clinical trial aimed to compare the dimensional dental arch changes after anterior open bite (AOB) treatment with bonded spurs associated with posterior build-ups vs bonded spurs alone.
Patients aged between 7 and 11 years with AOB were recruited at a university clinic and randomly allocated into 2 groups. The experimental group was treated with bonded spurs associated with posterior build-ups (SBU) and the comparison group with bonded spurs alone (S). Digital dental models were obtained at pretreatment and after 12 months of treatment. The overbite change was the primary outcome. The randomization list was obtained at the Web site www.randomization.com. Allocation concealment involved sequentially numbered, sealed, and opaque envelopes. The outcomes' assessment was blinded. Analysis of covariance was used for intergroup comparisons (P <0.05). Mean difference (MD) and 95% confidence interval (CI) were obtained.
Twenty-four patients (mean age, 8.22 ± 1.06 years; 7 males and 17 females) were included in the SBU group, and 25 patients (mean age, 8.30 ± 0.99 years; 11 males and 14 females) were included in the comparison group. After a 12-month follow-up, the overbite increased approximately 4 mm in both groups (MD, -0.11 mm; 95% CI, -1.03 to 0.80). Means of anterior dentoalveolar vertical development ranged from 2.24 mm (S group) to 2.49 mm (SBU group) and from 1.31 mm (SBU group) to 1.55 mm (S group) for the maxilla (MD, -0.24 mm; 95% CI, -0.91 to 0.44) and mandible (MD, 0.29 mm; 95% CI, -0.39 to 0.96), respectively. The maxillary intermolar distance decreased in the SBU group and increased in the S group (MD, -0.48 mm; 95% CI, -0.92 to -0.03). The mandibular intermolar distance increased in the SBU group and decreased in the comparison group (MD, 0.26 mm; 95% CI, 0.004-0.52). Plaque accumulation around the spurs was observed in some patients.
Both protocols demonstrated similar improvements in the AOB with similar effects on the dental arches. The SBU group showed a slight decrease in the maxillary intermolar distance and a slight increase in the mandibular intermolar distance, whereas opposite changes were observed for the S group.
This trial was registered at Clinicaltrials.gov (Identifier NCT03702881).
The study protocol was not published.
This work was supported by the São Paulo Research Foundation (FAPESP) grants nos. 2017/06440-3, 2018/05238-9, and 2018/24003-2; and financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES), Finance Code 001.
本研究为单中心、2 臂、平行组随机临床试验，旨在比较前牙开（AOB）治疗中使用带后牙加高的粘结支抗（SBU）与单独使用粘结支抗（S）后的牙弓三维变化。
在大学诊所招募了年龄在 7 至 11 岁之间患有 AOB 的患者，并将其随机分配到 2 组。实验组接受带后牙加高的粘结支抗（SBU）治疗，对照组接受单独使用粘结支抗（S）治疗。在治疗前和治疗 12 个月后获取数字牙模。覆的变化为主要结果。随机分组清单可在网站 www.randomization.com 获得。分组隐匿涉及按顺序编号、密封和不透明的信封。结果评估是盲法的。使用协方差分析进行组间比较（P<0.05）。获得了平均值差（MD）和 95%置信区间（CI）。
共有 24 名患者（平均年龄 8.22±1.06 岁；7 名男性和 17 名女性）被纳入 SBU 组，25 名患者（平均年龄 8.30±0.99 岁；11 名男性和 14 名女性）被纳入对照组。在 12 个月的随访后，两组的覆都增加了约 4mm（MD，-0.11mm；95%CI，-1.03 至 0.80）。上前牙牙槽垂直发育的平均值范围为 2.24mm（S 组）至 2.49mm（SBU 组）和 1.31mm（SBU 组）至 1.55mm（S 组）上颌（MD，-0.24mm；95%CI，-0.91 至 0.44）和下颌（MD，0.29mm；95%CI，-0.39 至 0.96）。SBU 组上颌磨牙间距离减小，S 组增大（MD，-0.48mm；95%CI，-0.92 至 -0.03）。SBU 组下颌磨牙间距离增加，对照组减少（MD，0.26mm；95%CI，0.004-0.52）。一些患者的支抗周围有菌斑堆积。
两种方案都显示出 AOB 的相似改善，对牙弓的影响也相似。SBU 组上颌磨牙间距离略有减小，下颌磨牙间距离略有增加，而 S 组则相反。
本试验在 Clinicaltrials.gov 注册（标识符 NCT03702881）。
研究方案未公布。
本工作得到了巴西圣保罗研究基金会（FAPESP）项目的支持，分别为 2017/06440-3、2018/05238-9 和 2018/24003-2；并部分由巴西高等教育人员协调委员会（CAPES）资助，资金代码 001。
