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食管手术后婴幼儿及儿童下食管括约肌功能的评估

Evaluation of lower esophageal sphincter function in infants and children following esophageal surgery.

作者信息

Takano K, Iwafuchi M, Uchiyama M, Yagi M, Ueno A, Iwasaki M

机构信息

Department of Pediatric Surgery, Niigata University Hospital, Japan.

出版信息

J Pediatr Surg. 1988 May;23(5):410-4. doi: 10.1016/s0022-3468(88)80436-6.

Abstract

Esophageal manometry was performed before and after the operations for esophageal disorders in children to evaluate lower esophageal sphincter (LES) function and motility of the esophagocardiac region in each disease. Patients who underwent radical operations for gross C-type esophageal atresia (EA) and those with hiatal hernias considered to have gastroesophageal reflux (GER) showed reduction in LESP and LESL and eosphagocardiac motor abnormalities. Lower esophageal sphincter pressure and length, and motility of the esophagocardiac region improved in six patients who underwent an antireflux operation. Abnormal esophageal waves in EA patients persisted even after improvements in LES function by the antireflux operation and were considered to be a congenital problem, as the literature suggests. Effects of surgical intervention on the esophagus on the LES function were studied. Lower esophageal sphincter and esophagocardiac function were preserved, and GER did not develop after Livaditis' procedure for EA or esophageal transection and sectioning the esophageal branch of the vagus nerve for esophageal varices. Anatomic abnormalities that lead to LES dysfunction are considered to cause GER.

摘要

对患有食管疾病的儿童在手术前后进行食管测压,以评估每种疾病中食管下括约肌(LES)功能及食管贲门区域的运动功能。接受根治性手术治疗严重C型食管闭锁(EA)的患者以及被认为有胃食管反流(GER)的食管裂孔疝患者,其LES压力(LESP)和LES长度(LESL)降低,且食管贲门运动异常。6例接受抗反流手术的患者,其食管下括约肌压力、长度以及食管贲门区域的运动功能得到改善。正如文献所提示的,EA患者即使在抗反流手术使LES功能改善后,异常食管波仍持续存在,被认为是先天性问题。研究了手术干预食管对LES功能的影响。在Livaditis治疗EA的手术或为治疗食管静脉曲张而进行食管横断及切断迷走神经食管支后,食管下括约肌和食管贲门功能得以保留,且未发生GER。导致LES功能障碍的解剖学异常被认为会引起GER。

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